Analyzing the regulation of metabolic pathways in human breast cancer.

Schramm G, Surmann EM, Wiesberg S, Oswald M, Reinelt G, Eils R, König R (2010) Analyzing the regulation of metabolic pathways in human breast cancer. BMC Med Genomics 3, 39. PubMed

Abstract

Tumor therapy mainly attacks the metabolism to interfere the tumor's anabolism and signaling of proliferative second messengers. However, the metabolic demands of different cancers are very heterogeneous and depend on their origin of tissue, age, gender and other clinical parameters. We investigated tumor specific regulation in the metabolism of breast cancer.

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doi: 10.1186/1755-8794-3-39 PMID: 20831783