Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms.

König R, Schramm G, Oswald M, Seitz H, Sager S, Zapatka M, Reinelt G, Eils R (2006) Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms. BMC Bioinformatics 7, 119.

Abstract

Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information needs to be extracted in a reasonable way and funneled into manageable and functionally meaningful patterns. Genes may be reasonably combined using knowledge about their interaction behaviour. On a proteomic level, biochemical research has elucidated an increasingly complete image of the metabolic architecture, especially for less complex organisms like the well studied bacterium Escherichia coli.

Beteiligte Forschungseinheiten

Netzwerkmodellierung

Leibniz-HKI-Autor*innen

Rainer König
Marcus Oswald

Identifier

PMID: 16524469