Microbial natural products serving as mediators of biological communication are essential for our lives. They do, however, play an ambivalent role: on the one hand, they contribute to the generation of many infectious diseases; on the other hand, they belong to the most important sources provided in drugs such as antibiotics. 

We investigate the communication between micro-organisms to be able to make use of the acquired know-how to develop innovative components for the diagnosis and therapy of diseases. By means of implementing those research results and the derived models thereof, we make a contribution to the development of the systems biology of an infection.

Successful explorer of active compounds // 10.12.2014

Natural product researcher Prof. Dr. Christian Hertweck from Jena receives the Leibniz Prize of the German Research Foundation (DFG) more…

Fighting Infections Side by Side // 02.12.2014

The Leibniz ScienceCampus InfectoOptics unites biologists, physicists and chemists in combating infectious diseases more…

Honour for excellent PhD thesis // 27.11.2014

Dissertation Award of the Leibniz Association for Tom Bretschneider more…


13.01.2015 // 13:00 - 14:30 Uhr // Lecture hall Robert Koch, HKI-Center for Systems Biology of Infection

SFB TR 124 FungiNet - Colloquium

14.01.2015 // 16:15 Uhr // Lecture Hall Louis Pasteur, HKI-Center for Systems Biology of Infection

Robert Altwasser:
Gene regulatory network inference in human pathogenic fungi

16.01.2015 // 09:00 - 13:00 Uhr // Lecture hall Nucleus, Leibniz Institute for Age Research - Fritz Lipmann Institute

Symposium on Molecular Signaling in Health and Disease


Schwartze VU, Winter S, Shelest E, Marcet-Houben M, Horn F, Wehner S, Linde J, Valiante V, Sammeth M, Riege K, Nowrousian M, Kaerger K, Jacobsen ID, Marz M, Brakhage AA, Gabaldón T, Böcker S, Voigt K

Gene expansion shapes genome architecture in the human pathogen Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient terrestrial Mucorales (Mucoromycotina). PLoS Genetics

Linde J, Duggan S, Weber M, Horn F, Sieber P, Hellwig D, Riege K, Marz M, Martin R, Guthke R, Kurzai O

Defining the transcriptomic landscape of Candida glabrata by RNA-Seq. Nucleic Acids Research [Accepted]