Microbial natural products serving as mediators of biological communication are essential for our lives. They do, however, play an ambivalent role: on the one hand, they contribute to the generation of many infectious diseases; on the other hand, they belong to the most important sources provided in drugs such as antibiotics. 

We investigate the communication between micro-organisms to be able to make use of the acquired know-how to develop innovative components for the diagnosis and therapy of diseases. By means of implementing those research results and the derived models thereof, we make a contribution to the development of the systems biology of an infection.

Innovations against infections // 16.03.2015

Doctoral Researchers of the consortium InfectControl 2020 join forces in fighting and preventing infectious diseases more…

Interdisciplinary team on the hunt for new active compounds // 13.03.2015

President of the Leibniz Association opens Research Cluster funded by the Federal Ministry for Education and Research more…

Fighting Infections Side by Side // 16.02.2015

Kick-off Meeting of the Leibniz Science Campus InfectoOptics more…


01.04.2015 // 14:15 Uhr // Lecture Hall Louis Pasteur, HKI-Center for Systems Biology of Infection

Prof. Dr. Ivo Große:
Treasure hunt without treasure map – de-novo motif discovery in the jungle of DNA and RNA sequences

01.04.2015 // 16:15 Uhr // Lecture Hall Louis Pasteur, HKI-Center for Systems Biology of Infection

Konrad Grützmann:
Combinatorial Biological Complexity - A study of amino acid side chains and alternative splicing

13.04.2015 - 16.04.2015 // Rosensäle, Friedrich Schiller-University Jena

5th International Student Conference on Microbial Communication


Schwartze VU, Winter S, Shelest E, Marcet-Houben M, Horn F, Wehner S, Linde J, Valiante V, Sammeth M, Riege K, Nowrousian M, Kaerger K, Jacobsen ID, Marz M, Brakhage AA, Gabaldón T, Böcker S, Voigt K

Gene expansion shapes genome architecture in the human pathogen Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient terrestrial Mucorales (Mucoromycotina). PLoS Genetics