Microbial natural products serving as mediators of biological communication are essential for our lives. They do, however, play an ambivalent role: on the one hand, they contribute to the generation of many infectious diseases; on the other hand, they belong to the most important sources provided in drugs such as antibiotics. 

We investigate the communication between micro-organisms to be able to make use of the acquired know-how to develop innovative components for the diagnosis and therapy of diseases. By means of implementing those research results and the derived models thereof, we make a contribution to the development of the systems biology of an infection.

Honour for excellent PhD thesis // 27.11.2014

Dissertation Award of the Leibniz Association for Tom Bretschneider more…

New knowledge about ancient pathogen // 14.11.2014

Scientists from Jena decode the genome of Lichtheimia corymbifera more…

Fraternization on a small scale // 13.11.2014

Research on fungus-bacteria interactions published in eLife more…

More than just yoghurt // 12.11.2014

Funding for FunComPath by European Programme more…


01.12.2014 // 16:00 Uhr // Lecture Hall Louis Pasteur, HKI-Center for Systems Biology of Infection

Sven Micklisch:
Funktionelle Charakterisierung von Age-Related Maculopathy Susceptibility 2 - ARMS2

02.12.2014 - 03.12.2014 // Lecture hall Koch and Pasteur, HKI Center for Systems Biology of Infection

Biotechnology of Natural Products

03.12.2014 // 19:00 Uhr // Lecture hall Erbertstraße

Dr. Knut Drescher:
Biophysics of Biofilms


Schwartze VU, Winter S, Shelest E, Marcet-Houben M, Horn F, Wehner S, Linde J, Valiante V, Sammeth M, Riege K, Nowrousian M, Kaerger K, Jacobsen ID, Marz M, Brakhage AA, Gabaldón T, Böcker S, Voigt K

Gene expansion shapes genome architecture in the human pathogen Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient terrestrial Mucorales (Mucoromycotina). PLoS Genetics

Wartenberg A, Linde J, Martin R, Schreiner M, Horn F, Jacobsen ID, Jenull S, Wolf T, Kuchler K, Guthke R, Kurzai O, Forche A, d’Enfert C, Brunke S, Hube B

Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant. PLoS Genetics [Accepted]