Microbial natural products serving as mediators of biological communication are essential for our lives. They do, however, play an ambivalent role: on the one hand, they contribute to the generation of many infectious diseases; on the other hand, they belong to the most important sources provided in drugs such as antibiotics. 

We investigate the communication between micro-organisms to be able to make use of the acquired know-how to develop innovative components for the diagnosis and therapy of diseases. By means of implementing those research results and the derived models thereof, we make a contribution to the development of the systems biology of an infection.

Successful explorer of active compounds // 10.12.2014

Natural product researcher Prof. Dr. Christian Hertweck from Jena receives the Leibniz Prize of the German Research Foundation (DFG) more…

Fighting Infections Side by Side // 02.12.2014

The Leibniz ScienceCampus InfectoOptics unites biologists, physicists and chemists in combating infectious diseases more…

Honour for excellent PhD thesis // 27.11.2014

Dissertation Award of the Leibniz Association for Tom Bretschneider more…


19.12.2014 // 11:15 Uhr // Lecture Hall Louis Pasteur, HKI-Center for Systems Biology of Infection

Anne-Catrin Letzel:
Genome Mining von anaeroben Bakterien zur Entdeckung von Wirkstoffen

13.01.2015 // 13:00 - 14:30 Uhr // Lecture hall Robert Koch, HKI-Center for Systems Biology of Infection

SFB TR 124 FungiNet - Colloquium

14.01.2015 // 16:15 Uhr // Lecture Hall Louis Pasteur, HKI-Center for Systems Biology of Infection

Robert Altwasser:
Gene regulatory network inference in human pathogenic fungi


Schwartze VU, Winter S, Shelest E, Marcet-Houben M, Horn F, Wehner S, Linde J, Valiante V, Sammeth M, Riege K, Nowrousian M, Kaerger K, Jacobsen ID, Marz M, Brakhage AA, Gabaldón T, Böcker S, Voigt K

Gene expansion shapes genome architecture in the human pathogen Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient terrestrial Mucorales (Mucoromycotina). PLoS Genetics