Microbial natural products serving as mediators of biological communication are essential for our lives. They do, however, play an ambivalent role: on the one hand, they contribute to the generation of many infectious diseases; on the other hand, they belong to the most important sources provided in drugs such as antibiotics. 

We investigate the communication between micro-organisms to be able to make use of the acquired know-how to develop innovative components for the diagnosis and therapy of diseases. By means of implementing those research results and the derived models thereof, we make a contribution to the development of the systems biology of an infection.

INFECTIONS'21 // 20.01.2015

Start of a new Leibniz Research Alliance more…

Prof. Dr. Oliver Kurzai is the new speaker of the Center for Innovation Competence Septomics in Jena. Quelle: HKI/Schroll

New Speaker for Septomics // 14.01.2015

Executive Board of the Center elects Prof. Dr. Oliver Kurzai more…

Successful explorer of active compounds // 10.12.2014

Natural product researcher Prof. Dr. Christian Hertweck from Jena receives the Leibniz Prize of the German Research Foundation (DFG) more…


29.01.2015 // 11:00 Uhr // Lecture hall Robert Koch & Louis Pasteur, HKI-Center for Systems Biology of Infection

Prof. Dr. Michael Freitag:
Chromatin structure controls expression of secondary metabolism

10.02.2015 // 13:00 - 14:30 Uhr // Lecture hall Robert Koch, HKI-Center for Systems Biology of Infection

SFB TR 124 FungiNet - Colloquium

10.02.2015 // 14:15 Uhr // Lecture hall Louis Pasteur, HKI-Center for Systems Biology of Infection

Claudia Roß:
Toxinbiosynthese von Burkholderia spp. in Interaktionen mit Pilzen, Pflanzen und Insekten


Schwartze VU, Winter S, Shelest E, Marcet-Houben M, Horn F, Wehner S, Linde J, Valiante V, Sammeth M, Riege K, Nowrousian M, Kaerger K, Jacobsen ID, Marz M, Brakhage AA, Gabaldón T, Böcker S, Voigt K

Gene expansion shapes genome architecture in the human pathogen Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient terrestrial Mucorales (Mucoromycotina). PLoS Genetics

Linde J, Duggan S, Weber M, Horn F, Sieber P, Hellwig D, Riege K, Marz M, Martin R, Guthke R, Kurzai O

Defining the transcriptomic landscape of Candida glabrata by RNA-Seq. Nucleic Acids Research [Accepted]