Microbial natural products serving as mediators of biological communication are essential for our lives. They do, however, play an ambivalent role: on the one hand, they contribute to the generation of many infectious diseases; on the other hand, they belong to the most important sources provided in drugs such as antibiotics. 

We investigate the communication between micro-organisms to be able to make use of the acquired know-how to develop innovative components for the diagnosis and therapy of diseases. By means of implementing those research results and the derived models thereof, we make a contribution to the development of the systems biology of an infection.


08.07.2015 // 09:15 Uhr // Lecture hall Louis Paster, HKI Center for Systems Biology of Infection

Jakob Franke:
Genome Mining-Based Identification and Study of Natural Products from the Human Pathogenic Burkholderia mallei Group

10.07.2015 // 11:00 Uhr // Lecture hall Louis Pasteur, HKI-Center for Systems Biology of Infection

Dr. Gerald Lackner:
Polyketide and Peptide Biosynthesis in Symbiotic and Pathogenic Microbes

10.07.2015 // 11:35 Uhr // Lecture hall Louis Pasteur, HKI-Center for Systems Biology of Infection

Dr. Hajo Kries:
Tailor-made natural product synthetases


Schwartze VU, Winter S, Shelest E, Marcet-Houben M, Horn F, Wehner S, Linde J, Valiante V, Sammeth M, Riege K, Nowrousian M, Kaerger K, Jacobsen ID, Marz M, Brakhage AA, Gabaldón T, Böcker S, Voigt K

Gene expansion shapes genome architecture in the human pathogen Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient terrestrial Mucorales (Mucoromycotina). PLoS Genetics