Microbial natural products serving as mediators of biological communication are essential for our lives. They do, however, play an ambivalent role: on the one hand, they contribute to the generation of many infectious diseases; on the other hand, they belong to the most important sources provided in drugs such as antibiotics. 

We investigate the communication between micro-organisms to be able to make use of the acquired know-how to develop innovative components for the diagnosis and therapy of diseases. By means of implementing those research results and the derived models thereof, we make a contribution to the development of the systems biology of an infection.

Conflict under control // 17.11.2015

eLife publication shows fungal secondary metabolite is regulated by environment. more…

Old substance in a new guise // 12.11.2015

Angewandte Chemie International Edition reports promising compound - discovered at Jena's Hans Knöll Institute more…

Living in a lethal atmosphere // 06.11.2015

Science publication airs new capabilities of a potato pathogen more…

Imaginative fungi // 04.11.2015

HKI scientists receive medac research award 2015 more…


02.12.2015 // 19:00 Uhr // Lecture hall Erbertstraße

Prof. Dr. Mohamed A. Marahiel:
The NRPS assembly line machinery

08.12.2015 // 18:00 Uhr // Lecture Hall Am Planetarium 1

Dr. Aline Koch:
Towards an RNAi-based control of plant diseases

10.12.2015 // 16:00 Uhr // Nucleus, FLI New Building Entrance Hall, Beutenbergstraße 11

Anton Gartner:
Midlife-crisis; worrying about ageing; exploring and exploiting C. elegans worms


Schwartze VU, Winter S, Shelest E, Marcet-Houben M, Horn F, Wehner S, Linde J, Valiante V, Sammeth M, Riege K, Nowrousian M, Kaerger K, Jacobsen ID, Marz M, Brakhage AA, Gabaldón T, Böcker S, Voigt K

Gene expansion shapes genome architecture in the human pathogen Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient terrestrial Mucorales (Mucoromycotina). PLoS Genetics