Prof. Dr. Gianni Panagiotou

Microbiome Dynamics · Leitung +49 3641 532-1759 gianni.panagiotou@leibniz-hki.de

Curriculum vitae

Forschungsschwerpunkte

Medizinische & Umweltmetagenomik: Mensch, Maus, Pflanzen, marine Lebewesen
Systembiologie: Integration von –omics-Daten; Molekül/ Protein & Protein/ Protein Netzwerke
Synthetische Biologie: Metabolische Modellierung auf Genomausmaß, Design von Probiotika, Entdeckung von Postbiotika

Publikationen

Zhou Z^*, Kleis L^*, Depetris-Chauvin A^*, Jaskulski S, Damerell V, Michels KB, Gigic B, Nöthlings U^#, Panagiotou G^# (2024) Beneficial microbiome and diet interplay in early-onset colorectal cancer. EMBO Mol Med [Accepted]

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Brandt P^*, Mirhakkak MH^*, Wagner L, Driesch D, Möslinger A, Fänder P, Schäuble S, Panagiotou G, Vylkova S^# (2023) High-throughput profiling of Candida auris isolates reveals clade-specific metabolic differences. Microbiol Spectr 11(3), e0049823. (Review)

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Chao YY, Puhach A, Frieser D, Arunkumar M, Lehner L, Seeholzer T, Garcia-Lopez A, van der Wal M, Fibi-Smetana S, Dietschmann A, Sommermann T, Ćiković T, Taher L, Gresnigt MS, Vastert SJ, van Wijk F, Panagiotou G, Krappmann D, Groß O, Zielinski CE (2023) Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation. Nat Immunol 24(2), 295-308.

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Chen J^*, Leal Siliceo S^*, Ni Y, Nielsen HB, Xu A, Panagiotou G (2023) Identification of robust and generalizable biomarkers for microbiome-based stratification in lifestyle interventions. Microbiome 11(1), 178.

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Csader S^*, Chen X^*, Leung H^*, Männistö V, Pentikäinen H, Tauriainen MM, Savonen K, El-Nezami H, Schwab U^#, Panagiotou G^# (2023) Gut ecological networks reveal associations between bacteria, exercise and clinical profile in non-alcoholic fatty liver disease patients. mSystems 8(5), e0022423.

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Häder A^#, Schäuble S^#, Gehlen J, Thielemann N, Buerfent BC, Schüller V, Hess T, Wolf T, Schröder J, Weber M, Hünniger K, Löffler J, Vylkova S, Panagiotou G, Schumacher J, Kurzai O (2023) Pathogen-specific innate immune response patterns are distinctly affected by genetic diversity. Nat Commun 14(1), 3239.

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Kelani AA, Bruch A, Rivieccio F, Visser C, Krüger T, Weaver D, Pan X, Schaeuble S, Panagiotou G, Kniemeyer O, Bromley MJ, Bowyer P, Barber AE, Brakhage AA, Blango MG (2023) Disruption of the A. fumigatus RNA interference machinery alters the conidial transcriptome. RNA 29(7), 1033-1050.

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Leung H, Xiong L, Ni Y, Busch A, Bauer M, Press AT, Panagiotou G (2023) Impaired flux of bile acids from the liver to the gut reveals microbiome-immune interactions associated with liver damage. NPJ Biofilms and microbiomes 9(1), 35.

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Mirhakkak MH^*, Chen X^*, Heinekamp T, Sae-Ong T, Xu LL, Ni Y, Kurzai O, Barber AE, Brakhage AA, Boutin S, Schäuble S^#, Panagiotou G^# (2023) Genome-scale Metabolic modeling of Aspergillus fumigatus strains reveals growth dependencies on the lung microbiome. Nat Commun 14(1), 4369.

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Ni Y^*, Qian L^*, Leal Siliceo S^*, Long X^*, Nychas E, Liu Y, Ismaiah MJ, Leung H, Zhang L, Gao Q, Wu Q, Zhang Y, Jia Xi, Liu S, Yuan R, Zhou L, Wang X, Li Q, Zhao Y, El-Nezami H, Xu A, Xu G^#, Li H^#, Panagiotou G^#, Jia W^# (2023) Resistant starch decreases intrahepatic triglycerides in NAFLD patients via gut microbiome alterations. Cell Metab 35(9), 1530-1547.

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