(2025)
Candida albicans biofilm extracellular vesicles deliver candidalysin to epithelial cell membranes and induce host cell responses.
Infect Immun ,
e0040424.

Dr. Stefanie Allert
Mikrobielle Pathogenitätsmechanismen +49 3641 532-1141 stefanie.allert@leibniz-hki.deThemenfelder
Publikationen
(2024)
A highly conserved tRNA modification contributes to C. albicans filamentation and virulence.
Microbiol Spectr 12(5),
e0425522.
(2024)
The hyphal-specific toxin candidalysin promotes fungal gut commensalism.
Nature 627(8004),
620-627.
(2024)
Secretion of the fungal toxin candidalysin is dependent on conserved precursor peptide sequences.
Nat Microbiol 9(3),
669-683.
(2024)
Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκBmediated barrier protection.
PLOS Pathog 20(3),
e1012031.
(2024)
Nanobody-mediated neutralization of candidalysin prevents epithelial damage and inflammatory responses that drive vulvovaginal candidiasis pathogenesis.
mBio 15(3),
e0340923.
(2022)
From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris.
Virulence 13(1),
191-214.
(2022)
Candidalysin is the hemolytic factor of Candida albicans.
Toxins (Basel) 14(12),
874.
(2022)
Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion.
Cell Rep 38(1),
110187.
(2021)
A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis.
PLOS Pathog 17(9),
e1009884.