(2016)
Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids.
MBio 7(6),
Dr. Slavena Vylkova
Host Fungal Interfaces · Leitung +49 3641 532-1473 Slavena.Vylkova@leibniz-hki.deCurriculum vitae
Forschungsschwerpunkte
- Molekulare Zusammenhänge zwischen Stoffwechsel und Virulenz bei pathogenen Candida spp.
- Die Rolle von Stoffwechselsignalen bei der Etablierung mikrobieller Gemeinschaften
- Infektionsmodelle der Candidose
Wissenschaftlicher Werdegang
seit 2016 | NWG-Leiterin, NWG Host Fungal Interfaces, ZIK Septomics, Friedrich-Schiller-Universität Jena |
2014-2016 | Assistant Professor-Research, University of Texas Health Science Center at Houston, Houston, TX, USA |
2012-2016 | Adjunct Faculty, University of Houston-Downtown, Houston, TX, USA |
2013-2014 | Senior Research Associate, University of Texas Health Science Center at Houston, Houston, TX, USA |
2007-2013 | Post-doctoral fellow, University of Texas Health Science Center at Houston, Houston, TX, USA |
2007 | Ph.D., State University of New York at Buffalo, Buffalo, NY, USA |
2006-2007 | Wissenschaftliche Mitarbeiterin (PostDoc), Ottawa Health Research institute, Centre for Cancer Research, Ottawa, ON, Canada |
2002-2006 | Wissenschaftliche Mitarbeiterin, State University of New York at Buffalo, Department of Oral Biology, Buffalo, NY, USA |
2004 | M.Sc., State University of New York at Buffalo, Buffalo, NY, USA |
2004 | Wissenschaftliche Mitarbeiterin, State University of New York at Buffalo, Physiology Department Buffalo, NY, USA |
2001 | M.Sc., Sofia University, Sofia, Bulgaria |
Auszeichnungen · Ämter · wissenschaftliche Aktivitäten
seit 2021 | Editor, Microbiology Spectrum |
seit 2018 | Editor, Frontiers in Microbiology |
2014 | Judge Travel Grant, Annual Biomedical Research Conference for Minority Students, San Antonio, TX, USA |
2014 | ISHAM Young Fellow Travel Award, American society for Microbiology, 12th ASM Conference on Candida and Candidiasis, New Orleans, LA, USA |
2011 | Office of the Dean of McGovern Medical School Postdoctoral Fellow Travel Grant, University of Texas Health Science Center Houston, Houston, TX, USA |
Publikationen
(2014)
Modulation of phagosomal pH by Candida albicans promotes hyphal morphogenesis and requires Stp2p, a regulator of amino acid transport.
PLOS Pathog 10(3),
e1003995.
(2011)
The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH.
MBio 2(3),
e00055.
(2009)
Conservation and dispersion of sequence and function in fungal TRK potassium transporters: focus on Candida albicans.
FEMS Yeast Res 9(2),
278-292.
(2008)
Role of acetyl coenzyme A synthesis and breakdown in alternative carbon source utilization in Candida albicans.
Eukaryot Cell 7(10),
1733-1741.
(2007)
Histatin 5 initiates osmotic stress response in Candida albicans via activation of the Hog1 mitogen-activated protein kinase pathway.
Eukaryot Cell 6(10),
1876-1888.
(2007)
Human beta-defensins kill Candida albicans in an energy-dependent and salt-sensitive manner without causing membrane disruption.
Antimicrob Agents Chemother 51(1),
154-161.
(2007)
The role of released ATP in killing Candida albicans and other extracellular microbial pathogens by cationic peptides.
Purinergic Signal 3(1-2),
91-97.
(2006)
Distinct antifungal mechanisms: beta-defensins require Candida albicans Ssa1 protein, while Trk1p mediates activity of cysteine-free cationic peptides.
Antimicrob Agents Chemother 50(1),
324-331.
(2004)
The TRK1 potassium transporter is the critical effector for killing of Candida albicans by the cationic protein, Histatin 5.
J Biol Chem 279(53),
55060-55072.