
Dr. Sandra Timme
Angewandte Systembiologie · FungiNet / JSMC
Telefon: +49 3641 532-1230 Telefax: +49 3641 532-2230 E-Mail: sandra.timme@leibniz-hki.de
- Thema der Doktorarbeit: "Agentenbasierte Modellierung von räumlich-zeitlichen Interaktionen zwischen Immunzellen und human-pathogenen Pilzen"
- agentenbasierte Modellierung und Simulation von Wirt-Pathogen Interaktionen
- Interaktion von Immunzellen und Candida albicans im menschlichen Blut
- Migrationsdynamiken von Immunzellen in Folge von Pilzinfektionen
Wissenschaftlicher Werdegang
seit 2018 | Wissenschaftliche Mitarbeiterin in der Gruppe Angewandte Systembiology am Hans-Knöll-Institut |
2018 | Dr. rer. nat. in Bioinformatik an der Friedrich-Schiller-Universität Jena |
2013 | M.Sc. in Bioinformatik an der Friedrich-Schiller-Universität Jena |
2011 | B.Sc. in Bioinformatik an der Friedrich-Schiller-Universität Jena |
(2020) Hybrid agent-based modeling of Aspergillus fumigatus infection to quantitatively investigate the role of Pores of Kohn in human alveoli. Front Microbiol 11, 1951. Details PubMed Open Access
(2020) Ex vivo Immune profiling in patient blood enables quantification of innate immune effector functions. bioRxiv , Details Open Access PDF
(2019) Comparative assessment of aspergillosis by virtual infection modeling in murine and human lung. Front Immunol 10, 142. Details PubMed Open Access PDF Supplement
(2018) Predictive virtual infection modeling of fungal immune evasion in human whole blood. Front Immunol 9, 560. Details PubMed Open Access PDF Supplement
(2018) Quantitative simulations predict treatment strategies against fungal infections in virtual neutropenic patients. Front Immunol 9, 667. Details PubMed Open Access PDF Supplement
(2016) Deciphering the counterplay of Aspergillus fumigatus infection and host inflammation by evolutionary games on graphs. Sci Rep 6, 27807. Details PubMed Open Access PDF Supplement
(2015) Bottom-up modeling approach for the quantitative estimation of parameters in pathogen-host interactions. Frontiers in Microbiology 6(608), *authors contributed equally. Details PubMed Open Access
(2015) Image-based Systems Biology of Infection. Cytometry A 87(6), 462-470. Details PubMed