(2020)
The Laetiporus polyketide synthase LpaA produces a series of antifungal polyenes.
J Antibiot 73(10),
711-720.
Curriculum vitae
Forschungsschwerpunkte
- Biochemische und genetische Grundlagen des Sekundärstoffwechsels basaler Pilze (insbesondere Mucoromyceten und Zoopagomyceten)
- Pharmazeutische und ökologische Bedeutung der Naturstoffe aus basalen Pilzen
- alternative Naturstoffbiosynthese-Strategien
Wissenschaftlicher Werdegang
seit 2024 | Privatdozent am Institut für Pharmazie, Friedrich-Schiller-Universität, Jena |
2017-2024 | Habilitation (Pharmazeutische Mikrobiologie) an der Friedrich-Schiller-Universität Jena |
2015-2017 | Post-Doc, Institute Pasteur, Paris, Frankreich |
2009-2015 | Promotion (Biochemie) an der Friedrich-Schiller-Universität Jena und dem Hans-Knöll-Institut, Jena |
2003-2009 | Diplom (Biochemie/Molekularbiologie) an der Friedrich-Schiller-Universität Jena |
Publikationen
(2020)
Secretion of iron(III)-reducing metabolites during protein acquisition by the ectomycorrhizal fungus Paxillus involutus.
Microorganisms 9(1),
E35.
(2020)
Bacterial-like nonribosomal peptide synthetases produce cyclopeptides in the zygomycetous fungus Mortierella alpina.
Appl Env Microbiol 87(3),
e02051-20.
(2019)
Fungal biosurfactants from Mortierella alpina.
Org Lett 21(5),
1444-1448.
(2019)
Diversity and bioactivity of Armillaria sesquiterpene aryl ester natural products.
Mycol Prog 18(8),
1027-1037.
(2019)
Melleolides impact fungal translation via elongation factor 2.
Org Biomol Chem 17(19),
4906-4916.
(2016)
A non-canonical melanin biosynthesis pathway protects Aspergillus terreus conidia from environmental stress.
Cell Chem Biol 23(5),
587-597.
(2015)
A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster.
Front Microbiol 6,
184.
(2015)
Phytotoxin production in Aspergillus terreus is regulated by independent environmental signals.
eLife 4,
e07861.
(2014)
Terrein Biosynthesis in Aspergillus terreus and Its Impact on Phytotoxicity.
Chem Biol 21(6),
719-731.