Publikationen

Nützmann HW, Reyes-Dominguez Y, Scherlach K, Schroeckh V, Horn F, Gacek A, Schümann J, Hertweck C, Strauss J, Brakhage AA (2011) Bacteria-induced natural product formation in the fungus Aspergillus nidulans requires Saga/Ada-mediated histone acetylation. Proc Natl Acad Sci U S A 108(34), 14282-14287.
Regueira TB, Kildegaard KR, Hansen BG, Mortensen UH, Hertweck C, Nielsen J (2011) Molecular basis for mycophenolic acid biosynthesis in Penicillium brevicompactum. Appl Environ Microbiol 77(9), 3035-3043.
Scharf DH, Remme N, Habel A, Chankhamjon P, Scherlach K, Heinekamp T, Hortschansky P, Brakhage AA, Hertweck C (2011) A dedicated glutathione S-transferase mediates carbon-sulfur bond formation in gliotoxin biosynthesis. J Am Chem Soc 133(32), 12322-12325.
Scherlach K, Nützmann HW, Schroeckh V, Dahse HM, Brakhage AA, Hertweck C (2011) Cytotoxic pheofungins from an engineered fungus impaired in posttranslational protein modification. Angew Chem Int Ed 50(42), 9843-9847.
Scherlach K, Sarkar A, Schroeckh V, Dahse HM, Roth M, Brakhage AA, Horn U, Hertweck C (2011) Two induced fungal polyketide pathways converge into antiproliferative spiroanthrones. Chembiochem 12(12), 1836-1839.
Ueberschaar N, Ndejouong Ble S, Ding L, Maier A, Fiebig HH, Hertweck C (2011) Hydrazidomycins, cytotoxic alkylhydrazides from Streptomycesatratus. Bioorg Med Chem Lett 21(19), 5839-5841.
Vödisch M, Scherlach K, Winkler R, Hertweck C, Braun HP, Roth M, Haas H, Werner ER, Brakhage AA, Kniemeyer O (2011) Analysis of the Aspergillus fumigatus proteome reveals metabolic changes and the activation of the pseurotin A biosynthesis gene cluster in response to hypoxia. J Proteome Res 10(5), 2508-2524.
Weiz AR, Ishida K, Makower K, Ziemert N, Hertweck C, Dittmann E (2011) Leader peptide and a membrane protein scaffold guide the biosynthesis of the tricyclic peptide microviridin. Chem Biol 18(11), 1413-1421.
Winter JM, Behnken S, Hertweck C (2011) Genomics-inspired discovery of natural products. Curr Opin Chem Biol 15(1), 22-31.
Xu Z, Ding L, Hertweck C (2011) A branched extender unit shared between two orthogonal polyketide pathways in an endophyte. Angew Chem Int Ed Engl 50(20), 4667-4670.