Publikationen

Scharf DH, Remme N, Habel A, Chankhamjon P, Scherlach K, Heinekamp T, Hortschansky P, Brakhage AA, Hertweck C (2011) A dedicated glutathione S-transferase mediates carbon-sulfur bond formation in gliotoxin biosynthesis. J Am Chem Soc 133(32), 12322-12325.
Scherlach K, Nützmann HW, Schroeckh V, Dahse HM, Brakhage AA, Hertweck C (2011) Cytotoxic pheofungins from an engineered fungus impaired in posttranslational protein modification. Angew Chem Int Ed 50(42), 9843-9847.
Scherlach K, Sarkar A, Schroeckh V, Dahse HM, Roth M, Brakhage AA, Horn U, Hertweck C (2011) Two induced fungal polyketide pathways converge into antiproliferative spiroanthrones. Chembiochem 12(12), 1836-1839.
Ueberschaar N, Ndejouong Ble S, Ding L, Maier A, Fiebig HH, Hertweck C (2011) Hydrazidomycins, cytotoxic alkylhydrazides from Streptomycesatratus. Bioorg Med Chem Lett 21(19), 5839-5841.
Vödisch M, Scherlach K, Winkler R, Hertweck C, Braun HP, Roth M, Haas H, Werner ER, Brakhage AA, Kniemeyer O (2011) Analysis of the Aspergillus fumigatus proteome reveals metabolic changes and the activation of the pseurotin A biosynthesis gene cluster in response to hypoxia. J Proteome Res 10(5), 2508-2524.
Weiz AR, Ishida K, Makower K, Ziemert N, Hertweck C, Dittmann E (2011) Leader peptide and a membrane protein scaffold guide the biosynthesis of the tricyclic peptide microviridin. Chem Biol 18(11), 1413-1421.
Winter JM, Behnken S, Hertweck C (2011) Genomics-inspired discovery of natural products. Curr Opin Chem Biol 15(1), 22-31.
Xu Z, Ding L, Hertweck C (2011) A branched extender unit shared between two orthogonal polyketide pathways in an endophyte. Angew Chem Int Ed Engl 50(20), 4667-4670.
Zilliges Y, Kehr JC, Meissner S, Ishida K, Mikkat S, Hagemann M, Kaplan A, Börner T, Dittmann E (2011) The cyanobacterial hepatotoxin microcystin binds to proteins and increases the fitness of microcystis under oxidative stress conditions. PLOS One 6(3), e17615-e17615.
Zocher G, Richter ME, Müller U, Hertweck C (2011) Structural fine-tuning of a multifunctional cytochrome P450 monooxygenase. J Am Chem Soc 133(7), 2292-2302.