
Dr. Martin Roth
Biotechnikum
Telefon: +49 3641 532-1127 Telefax: +49 3641 532-2127 E-Mail: martin.roth@leibniz-hki.de
(2021) N-heterocyclization in gliotoxin biosynthesis is catalyzed by a distinct cytochrome P450 monooxygenase. Chembiochem 22(2), 336-339. Details PubMed Open Access PDF
(2020) Metabolic engineering of Amycolatopsis japonicum for optimized production of [S,S]-EDDS, a biodegradable chelator. Metab Eng 60, 148-156. Details PubMed
(2020) Optofluidic detection setup for multi-parametric analysis of microbiological samples in droplets. Biomicrofluidics 14(2), 024109. Details PubMed Open Access PDF
(2020) Monitoring and external control of pH in microfluidic droplets during microbial culturing. Microb Cell Fact 19(1), 16. Details PubMed Open Access PDF
(2019) Coding of experimental conditions in microfluidic droplet assays using colored beads and machine learning supported image analysis. Small 15(4), e1802384. Details PubMed
(2019) One sensor for multiple colors: Fluorescence analysis of microdroplets in microbiological screenings by frequency-division multiplexing. Anal Chem 91(4), 3055-3061. Details PubMed
(2018) Gold nanoparticle contact point density controls microbial adhesion on gold surfaces. Colloids Surf B Biointerfaces 163, 201-208. Details PubMed
(2018) Publisher Correction: Detection of antibiotics synthetized in microfluidic picolitre-droplets by various actinobacteria. Sci Rep 8(1), 15859. Details PubMed Open Access PDF
(2018) Genomics-driven discovery of a symbiont-specific cyclopeptide from bacteria residing in the rice seedling blight fungus. ChemBioChem 19(20), 2167-2172. Details PubMed
(2018) 3D-glass molds for facile production of complex droplet microfluidic chips. Biomicrofluidics 12(2), 024115. Details PubMed Open Access PDF
(2018) Critical physiological factors influencing the outcome of antimicrobial testing according to ISO 22196 / JIS Z 2801. PLOS One 13(3), e0194339. Details PubMed Open Access PDF
(2018) An integrated chip-mass spectrometry and epifluorescence approach for online monitoring of bioactive metabolites from incubated Actinobacteria in picoliter droplets. Anal Bioanal Chem 410(29), 7679-7687. Details PubMed Open Access PDF
(2017) Herpetopanone, a diterpene from Herpetosiphon aurantiacus discovered by isotope labeling. Beilstein J. Org. Chem. 13, 2458-2465. Details PDF
(2016) Nanorough titanium surfaces reduce adhesion of Escherichia coli and Staphylococcus aureus via nano adhesion points Colloids Surf B Biointerfaces 145, 617-625. Details PubMed
(2016) Zincophorin – biosynthesis in Streptomyces griseus and antibiotic properties GMS Infect Dis 4, Doc08. Details Open Access
(2015) Zwitterionic cellulose carbamate with regioselective substitution pattern: a coating material possessing antimicrobial activity Macromol Biosci 16(4), 522-534. Details PubMed
(2015) Enhanced and homogeneous oxygen availability during incubation of microfluidic droplets. RSC Advances 5, 101871-101878. Details Open Access PDF Supplement
(2015) Phytoremediation using microbially mediated metal accumulation in Sorghum bicolor Environ Sci Pollut Res 22(24), 19408-19416. Details PubMed
(2015) Insights into Structure–Activity Relationships of Bacterial RNA Polymerase Inhibiting Corallopyronin Derivatives J Nat Prod 78(10), 2505-2509. Details PubMed Supplement
(2015) Structure and absolute configuration of auriculamide, a natural product from the predatory bacterium Herpetosiphon aurantiacus. Eur J Org Chem 14, 3057-3062. Details
(2015) Plant pathogenic anaerobic bacteria use aromatic polyketides to access aerobic territory. Science 350(6261), 670-674. Details PubMed
(2015) A novel locus for mycelial aggregation forms a gateway to improved Streptomyces cell factories Microbial Cell Factories 14:44, Details Open Access PDF
(2014) Identification of hypoxia-inducible target genes of Aspergillus fumigatus by transcriptome analysis reveals cellular respiration as important contributor to hypoxic survival. Eukaryot Cell 13(9), 1241-1253. Details PubMed
(2014) Reproducible biofilm cultivation of chemostat-grown Escherichia coli and investigation of bacterial adhesion on biomaterials using a non-constant-depth film fermenter. PLOS One 9(1), e84837. Details PubMed Open Access PDF
(2014) New myxothiazols from the predatory bacterium Myxococcus fulvus. J Antibiot 67(7), 519-525. Details PubMed
(2014) Corallorazines from the myxobacterium Corallococcus coralloides. J Nat Prod 77(1), 159-163. Details PubMed Open Access PDF
(2014) Siderophore production by streptomycetes-stability and alteration of ferrihydroxamates in heavy metal-contaminated soil. Environ Sci Pollut Res Int 22(24), 19376-19383. Details PubMed
(2014) Growth of streptomycetes in soil and their impact on bioremediation. J Hazard Mater 267, 128-135. Details PubMed
(2013) Application of micro-segmented flow for two-dimensional characterization of the combinatorial effect of zinc and copper ions on metal-tolerant Streptomyces strains. Appl Microbiol Biotechnol 97(20), 8923-8930. Details PubMed
(2013) Physical vapor deposited titanium thin films for biomedical applications: Reproducibility of nanoscale surface roughness and microbial adhesion properties. Applied Surface Science 280, 578-589. Details
(2013) Live and death of streptomycetes in soil - what happens to the biomass? Journal of Plant Nutrition and Soil Science 176, 665-673. Details
(2013) Real-time image processing for label-free enrichment of Actinobacteria cultivated in picolitre droplets. Lab Chip 13(18), 3707-3713, *authors contributed equally. Details PubMed Open Access
(2012) Imaging mass spectrometry and genome mining reveal highly antifungal virulence factor of mushroom soft rot pathogen. Angew Chem Int Ed Engl 51(52), 13173-13177. Details PubMed
(2012) Biosynthesis of the respiratory toxin bongkrekic acid in the pathogenic bacterium Burkholderia gladioli. Chem Biol 19(9), 1164-1174. Details PubMed Open Access PDF
(2012) A microfluidics-based approach to drug discovery. Biomed Tech (Berl) 57(SI-1 Track-B), 270. Details
(2012) Differential expression of silent polyketide biosynthesis gene clusters in chemostat cultures of Aspergillus nidulans. J Biotechnol 160(1-2), 64-71. Details PubMed
(2012) Epidithiol formation by an unprecedented twin carbon-sulfur lyase in the gliotoxin pathway. Angew Chem Int Ed Engl 51(40), 10064-10068. Details PubMed
(2011) Two induced fungal polyketide pathways converge into antiproliferative spiroanthrones. Chembiochem 12(12), 1836-1839. Details PubMed
(2011) Analysis of the Aspergillus fumigatus proteome reveals metabolic changes and the activation of the pseurotin A biosynthesis gene cluster in response to hypoxia. J Proteome Res 10(5), 2508-2524. Details PubMed
(2010) Functionally distinct modules operate two consecutive alpha,beta-->beta,gamma double-bond shifts in the rhizoxin polyketide assembly line. Angew Chem Int Ed Engl 49(8), 1460-1464. Details PubMed
(2010) Closthioamide: an unprecedented polythioamide antibiotic from the strictly anaerobic bacterium Clostridium cellulolyticum. Angew Chem Int Ed Engl 49(11), 2011-2013. Details PubMed
(2010) Production and derivate composition of trisporoids in extended fermentation of Blakeslea trispora. Appl Microbiol Biotechnol 88(1), 241-249. Details PubMed
(2010) Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative aureothin analogues. J Am Chem Soc 132(30), 10407-10413. Details PubMed Open Access
(2009) Polyketide-chain branching by an enzymatic Michael addition. Angew Chem Int Ed Engl 48(27), 5001-5004. Details PubMed
(2008) Growth of keratinocytes on porous films of poly(3-hydroxybutyrate) and poly(4-hydroxybutyrate) blended with hyaluronic acid and chitosan. J Biomed Mater Res A 85(4), 1072-1081. Details PubMed
(2007) Rhizonin, the first mycotoxin isolated from the zygomycota, is not a fungal metabolite but is produced by bacterial endosymbionts. Appl Environ Microbiol 73(3), 793-797. Details PubMed Open Access PDF
(2007) Burkholderia rhizoxinica sp. nov. and Burkholderia endofungorum sp. nov., bacterial endosymbionts of the plant-pathogenic fungus Rhizopus microsporus. Int J Syst Evol Microbiol 57(Pt 11), 2583-2590. Details PubMed Open Access PDF Supplement
(2005) Cervimycin A-D: a polyketide glycoside complex from a cave bacterium can defeat vancomycin resistance. Chemistry 11(19), 5523-5530. Details PubMed
(2004) Digital reaction technology by micro segmented flow—components, concepts and applications Chemical Engineering Journal 101, 201-216. Details
(2003) Generation of larger numbers of separated microbial populations by cultivation in segmented-flow microdevices. Lab Chip 3(3), 202-207. Details PubMed