Huijuan Guo
Forschungsschwerpunkte
  • discovery of new bioactive secondary metabolites
  • structure elucidation of natural products
  • protein identification and analysis
Themenfelder
Curriculum vitae

Wissenschaftlicher Werdegang

2009-2014 Doctoral thesis in chemistry at the Max-Planck-Institute for Chemical Ecology, Jena
2007–2009 Research assistant at the Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China
2005-2007 Master thesis in natural product chemistry, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China
2004-2005 Master study in biochemistry and molecular biology, Graduate University of Chinese Academy of Science, Beijing, P. R. China
2000-2004 Bachelor study, Shenyang Agriculture University, Shenyang, P. R. China

Auszeichnungen · Ämter · wissenschaftliche Aktivitäten

2009-2014 International Leibniz Research School for Microbial and Biomolecular Interactions,
ILRS Jena, Germany
2009 - Gesellschaft Chinesischer Chemiker und Chemieingenieuer in der Bundesrepublik
Deutschland
Publikationen

Braga D, Last D, Hasan M, Guo H, Leichnitz D, Uzum Z, Richter I, Schalk F, Beemelmanns C, Hertweck C, Lackner G (2019) Metabolic pathway rerouting in Paraburkholderia rhizoxinica evolved long-overlooked derivatives of coenzyme F420. ACS Chem Biol 14(9), 2088-2094. Details PubMed

Guo H, Roman D, Beemelmanns C (2019) Tropolone natural products. Nat Prod Rep 36(8), 1137-1155. Details PubMed Open Access

Peña-Ortiz L, Graça A P, Guo H, Braga D, Köllner T G, Regestein L, Beemelmanns C, Lackner G (2019) Biosynthesis of the redox cofactor mycofactocin comprises oligoglycosylation by MftF in Mycolicibacterium smegmatis Details Open Access

Benndorf R, Guo H, Sommerwerk E, Weigel C, Garcia-Altares M, Martin K, Hu H, Kuefner M, de Beer ZW, Poulsen M, Beemelmanns C (2018) Natural products from Actinobacteria associated with fungus-growing termites. Antibiotics 7(3), pii: E83. Details PubMed Open Access

Guo H, Benndorf R, König S, Leichnitz D, Weigel C, Peschel G, Berthel P, Kaiser M, Steinbeck C, Werz O, Poulsen M, Beemelmanns C (2018) Expanding the Rubterolone Family: Intrinsic Reactivity and Directed Diversification of PKS‐derived Pyrans. Chem Eur J 24(44), 11319-11324. Details PubMed

Guo H, Schmidt A, Stephan P, Raguž L, Braga D; Kaiser M, Dahse HM, Weigel C, Lackner G, Beemelmanns C (2018) Precursor-directed Diversification of Cyclic Tetrapeptidic Pseudoxylallemycins. ChemBioChem 19(21), 2307-2311. Details PubMed

Rischer M, Raguz L, Guo H, Keiff F, Diekert G, Goris T, Beemelmanns C (2018) Biosynthesis, Synthesis and Activities of Barnesin A, a NRPS-PKS Hybrid Produced by an Anaerobic Epsilonproteobacterium. ACS Chem Biol 13(8), 1990-1995. Details PubMed

Guo H, Benndorf R, Leichnitz D, Klassen JL, Vollmers J, Görls H, Steinacker M, Weigel C, Dahse HM, Kaster AK, de Beer ZW, Poulsen M, Beemelmanns C (2017) Isolation, biosynthesis and chemical modifications of rubterolones A–F, rare tropolone alkaloids from Actinomadura sp. 5-2. Chem Eur J 23(39), 9338-9345. Details PubMed

Guo H, Rischer M, Sperfeld M, Weigel C, Menzel KD, Clardy J, Beemelmanns C (2017) Natural products and morphogenic activity of γ-Proteobacteria associated with the marine hydroid polyp Hydractinia echinata. Bioorg Med Chem 25(22), 6088-6097. Details PubMed

Beemelmanns C, Guo H, Rischer M, Poulsen M. (2016) Natural products from microbes associated with insects. Beilstein J Org Chem 12, 314-327. Details PubMed Open Access

Guo H, Kreuzenbeck NB, Otani S, Garcia-Altares M, Dahse HM, Weigel C, Aanen DK, Hertweck C, Poulsen M, Beemelmanns C (2016) Pseudoxylallemycins A-F, cyclic tetrapeptides with rare allenyl modifications isolated from Pseudoxylaria sp. X802: A competitor of fungus-growing termite cultivars. Org Lett 18, 3338-3341. Details PubMed

Rischer M, Klassen J, Wolf T, Guo H, Shelest E, Clardy J, Beemelmanns C (2016) Draft Genome Sequence of Shewanella sp. P1-14-1, a Bacterial Inducer of Settlement and Morphogenesis in Larvae of the Marine Hydroid Hydractinia Echinata Genome Announc 4(1), e00003-16. Details PubMed

Klassen JL, Rischer M, Wolf T, Guo H, Shelest E, Clardy J, Beemelmanns C (2015) Genome Sequences of Three Pseudoalteromonas Strains P1-8, P1-11 and P1-30 Isolated from the Marine Hydroid Hydractinia echinata Genome Announc. 3(6), e01380-15. Details PubMed

Klassen JL, Wolf T, Rischer M, Guo H, Shelest E, Clardy J, Beemelmanns C (2015) Draft Genome Sequences of Six Pseudoalteromonas sp. Strains P1-7a, P1-9, P1-13-1a, P1-16-1b, P1-25 and P1-26, which Induce Larval Settlement and Metamorphosis in Hydractinia echinata Genome Announc. 3(6), e01477-15. Details PubMed

Shao Y, Arias-Cordero E, Guo H, Bartram S, Boland W (2014) In vivo Pyro-SIP assessing active gut microbiota of the cotton leafworm, Spodoptera littoralis. PLOS One 9(1), e85948. Details PubMed

Guo H, Wielsch N, Hafke JB, Svatoš A, Mithöfer A, Boland W (2013) A porin-like protein from oral secretions of Spodoptera littoralis larvae induces defense-related early events in plant leaves. Insect Biochem Mol Biol 43(9), 849-858. Details PubMed

Chen Y, Guo H, Du Z, Liu XZ, Che Y, Ye X (2009) Ecology-based screen identifies new metabolites from a Cordyceps-colonizing fungus as cancer cell proliferation inhibitors and apoptosis inducers. Cell Prolif 42(6), 838-847. Details PubMed

Guo H, Sun B, Gao H, Chen X, Liu S, Yao X, Liu X, Che Y (2009) Diketopiperazines from the Cordyceps-colonizing fungus Epicoccum nigrum. J Nat Prod 72(12), 2115-2119. Details PubMed

Guo H, Sun B, Gao H, Niu S, Liu X, Yao X, Che Y (2009) Trichocladinols A–C, Cytotoxic Metabolites from a Cordyceps-Colonizing Ascomycete Trichocladium opacum Eur J Org Chem 32, 5525-5530. Details

Guo H, Hu H, Liu S, Liu X, Zhou Y, Che Y (2007) Bioactive p-terphenyl derivatives from a Cordyceps-colonizing isolate of Gliocladium sp. J Nat Prod 70(9), 1519-1521. Details PubMed

Hu H, Guo H, Li E, Liu X, Zhou Y, Che Y (2006) Decaspirones F-I, bioactive secondary metabolites from the saprophytic fungus Helicoma viridis. J Nat Prod 69(12), 1672-1675. Details PubMed