Isolation and Synthesis of a Bacterially Produced Inhibitor of Rosette Development in Choanoflagellates.

Cantley AM, Woznica A, Beemelmanns C, King N, Clardy J (2016) Isolation and Synthesis of a Bacterially Produced Inhibitor of Rosette Development in Choanoflagellates. J Am Chem Soc 138(13), 4326-4329. PubMed

Abstract

The choanoflagellate Salpingoeca rosetta is a microbial marine eukaryote that can switch between unicellular and multicellular states. As one of the closest living relatives of animals, this organism has become a model for understanding how multicellularity evolved in the animal lineage. Previously our laboratories isolated and synthesized a bacterially produced sulfonolipid that induces S. rosetta to form multicellular

Beteiligte Abteilungen und Gruppen
HKI-Autoren
Themenfelder
Identifier

PMID: 26998963