Falk Hillmann

Dr. Falk Hillmann

Evolution mikrobieller Interaktionen · Abteilungsleiter

Telefon: +49 3641 532-1445 Telefax: +49 3641 532-0803 E-Mail: falk.hillmann@leibniz-hki.de

Themenfelder
Publikationen

Ferling I, Dunn JD, Ferling A, Soldati T, Hillmann F (2019) Conidial melanin of the human pathogenic fungus Aspergillus fumigatus disrupts cell autonomous defenses in amoebae bioRxiv 730879, preprint. Details

Noßmann M, Boysen JM, Krüger T, König CC, Hillmann F, Munder T, Brakhage AA (2019) Yeast two-hybrid screening reveals a dual function for the histone acetyltransferase GcnE by controlling glutamine synthesis and development in Aspergillus fumigatus Curr Genet 65(2), 523-538. Details PubMed

Radosa S, Ferling I, Sprague JL, Westermann M, Hillmann F (2019) The different morphologies of yeast and filamentous fungi trigger distinct killing and feeding mechanisms in a fungivorous amoeba. Environ Microbiol 21(5), 1809-1820. Details PubMed

Radosa S, Sprague JL, Tóth R, Wolf T, Sprenger M, Brunke S, Panagiotou G, Linde J, Gácser A, Hillmann F (2019) Phagocytic predation by the fungivorous amoeba Protostelium aurantium targets metal ion and redox homeostasis bioRxiv 690503, preprint. Details

Hillmann F, Forbes G, Novohradská S, Ferling I, Riege K, Groth M, Marz M, Spaller T, Winckler T, Schaap P, Gloeckner G (2018) Multiple roots of fruiting body formation in Amoebozoa. Genome Biol Evol 10(2), 591-606. Details PubMed

Noßmann M, Pieper J, Hillmann F, Brakhage AA, Munder T (2018) Generation of an arginine-tRNA-adapted Saccharomyces cerevisiae strain for effective heterologous protein expression. Curr Genet 64(3), 589-598. Details PubMed

Novohradska S, Ferling I, Hillmann F (2017) Exploring virulence determinants of filamentous fungal pathogens through interactions with soil amoebae. Front Cell Infect Microbiol 7, 497. (Review) Details Open Access

Geib E, Gressler M, Viediernikova I, Hillmann F, Jacobsen ID, Nietzsche S, Hertweck C, Brock M (2016) A non-canonical melanin biosynthesis pathway protects Aspergillus terreus conidia from environmental stress. Cell Chem Biol 23(5), 587-597. Details PubMed

Hillmann F, Bagramyan K, Straßburger M, Heinekamp T, Hong TB, Bzymek KP, Williams JC, Brakhage AA, Kalkum M (2016) The crystal structure of peroxiredoxin Asp f3 provides mechanistic insight into oxidative stress resistance and virulence of Aspergillus fumigatus. Sci Rep 6, 33396. Details PubMed Open Access

Spaller T, Kling E, Glöckner G, Hillmann F, Winckler T (2016) Convergent evolution of tRNA gene targeting preferences in compact genomes. Mob DNA 7, 17. Details PubMed Open Access

Vaknin Y, Hillmann F, Iannitti R, Ben Baruch N, Sandovsky-Losica H, Shadkchan Y, Romani L, Brakhage A, Kniemeyer O, Osherov N (2016) Identification and characterization of a novel Aspergillus fumigatus rhomboid family putative protease RbdA involved in hypoxia sensing and virulence. Infect Immun 84(6), 1866-1878. Details PubMed

Hillmann F, Novohradská S, Mattern DJ, Forberger T, Heinekamp T, Westermann M, Winckler T, Brakhage AA (2015) Virulence determinants of the human pathogenic fungus Aspergillus fumigatus protect against soil amoeba predation. Environ Microbiol 17(8), 2858-2869. Details PubMed

Hillmann F, Shekhova E, Kniemeyer O (2015) Insights into the cellular responses to hypoxia in filamentous fungi. Curr Genet 61(3), 441-455. Details PubMed

Mattern DJ, Schoeler H, Weber J, Novohradská S, Kraibooj K, Dahse HM, Hillmann F, Valiante V, Figge MT, Brakhage AA (2015) Identification of the antiphagocytic trypacidin gene cluster in the human-pathogenic fungus Aspergillus fumigatus. Applied Microbiology and Biotechnology 99(23), 10151-10161. Details PubMed

Hillmann F, Linde J, Beckmann N, Cyrulies M, Strassburger M, Heinekamp T, Haas H, Guthke R, Kniemeyer O, Brakhage AA (2014) The novel globin protein fungoglobin is involved in low oxygen adaptation of Aspergillus fumigatus. Mol Microbiol 93(3), 539-553. Details PubMed

Kroll K, Pähtz V, Hillmann F, Vaknin Y, Schmidt-Heck W, Roth M, Jacobsen ID, Osherov N, Brakhage AA, Kniemeyer O (2014) Identification of hypoxia-inducible target genes of Aspergillus fumigatus by transcriptome analysis reveals cellular respiration as important contributor to hypoxic survival. Eukaryot Cell 13(9), 1241-1253. Details PubMed

Shopova I, Bruns S, Thywissen A, Kniemeyer O, Brakhage AA, Hillmann F (2013) Extrinsic extracellular DNA leads to biofilm formation and colocalizes with matrix polysaccharides in the human pathogenic fungus Aspergillus fumigatus. Front Microbiol 4, 141. Details PubMed

Hillmann F, Argentini M, Buddelmeijer N (2011) Kinetics and phospholipid specificity of apolipoprotein N-acyltransferase. J Biol Chem 286(32), 27936-27946. Details PubMed

Hillmann F, Döring C, Riebe O, Ehrenreich A, Fischer RJ, Bahl H (2009) The role of PerR in O2-affected gene expression of Clostridium acetobutylicum. J Bacteriol 191(19), 6082-6093. Details PubMed

Hillmann F, Riebe O, Fischer RJ, Mot A, Caranto JD, Kurtz DM, Bahl H (2009) Reductive dioxygen scavenging by flavo-diiron proteins of Clostridium acetobutylicum. FEBS Lett 583(1), 241-245. Details PubMed

Hillmann F, Fischer RJ, Saint-Prix F, Girbal L, Bahl H (2008) PerR acts as a switch for oxygen tolerance in the strict anaerobe Clostridium acetobutylicum. Mol Microbiol 68(4), 848-860. Details PubMed

Hillmann F, Fischer RJ, Bahl H (2006) The rubrerythrin-like protein Hsp21 of Clostridium acetobutylicum is a general stress protein. Arch Microbiol 185(4), 270-276. Details PubMed

May A, Hillmann F, Riebe O, Fischer RJ, Bahl H (2004) A rubrerythrin-like oxidative stress protein of Clostridium acetobutylicum is encoded by a duplicated gene and identical to the heat shock protein Hsp21. FEMS Microbiol Lett 238(1), 249-254. Details PubMed