(2025)
"Pour some sugar on me"-Environmental Candida albicans isolates and the evolution of increased pathogenicity and antifungal resistance through sugar adaptation.
PLoS Pathog 21(10),
e1013542.
Dr. Stefanie Allert
Mikrobielle Pathogenitätsmechanismen +49 3641 532-1141 stefanie.allert@leibniz-hki.deThemenfelder
Publikationen
(2025)
Candida albicans biofilm extracellular vesicles deliver candidalysin to epithelial cell membranes and induce host cell responses.
Infect Immun 93(5),
e0040424.
(2025)
Fungal determinants contributing to translocation of Candida albicans yeast cells through the intestinal epithelial barrier.
Microlife 6,
uqaf026.
(2024)
A highly conserved tRNA modification contributes to C. albicans filamentation and virulence.
Microbiol Spectr 12(5),
e0425522.
(2024)
The hyphal-specific toxin candidalysin promotes fungal gut commensalism.
Nature 627(8004),
620-627.
(2024)
Secretion of the fungal toxin candidalysin is dependent on conserved precursor peptide sequences.
Nat Microbiol 9(3),
669-683.
(2024)
Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκBmediated barrier protection.
PLOS Pathog 20(3),
e1012031.
(2024)
Nanobody-mediated neutralization of candidalysin prevents epithelial damage and inflammatory responses that drive vulvovaginal candidiasis pathogenesis.
mBio 15(3),
e0340923.
(2022)
From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris.
Virulence 13(1),
191-214.
(2022)
Candidalysin is the hemolytic factor of Candida albicans.
Toxins (Basel) 14(12),
874.