Curriculum vitae

Wissenschaftlicher Werdegang
seit 2017 Wissenschaftliche Mitarbeiterin in der Gruppe Angewandte Systembiology am Hans-Knöll-Institut
2018 Dr. rer. nat. in Bioinformatik an der Friedrich-Schiller-Universität Jena
2012 Diplom in Bioinformatik an der Friedrich-Schiller-Universität Jena

Publikationen

Kaden T, Alonso-Roman R, Akbarimoghaddam P, Mosig AS, Graf K, Raasch M, Hoffmann B, Figge MT, Hube B, Gresnigt MS (2024) Modeling of intravenous caspofungin administration using an intestine-on-chip reveals altered Candida albicans microcolonies and pathogenicity. Biomaterials 307, 122525.
Battista M, Hoffmann B, Bachelot Y, Zimmermann L, Teuber L, Jost A, Linde S, Westermann M, Müller MM, Slevogt H, Hammerschmidt S, Figge MT, Vilhena C*#, Zipfel PF*# (2023) The role of pneumococcal extracellular vesicles on the pathophysiology of the kidney disease hemolytic uremic syndrome. mSphere 8(4), e0014223.
Hoffmann B*, Gerst R*, Cseresnyés Z, Foo W, Sommerfeld O, Press AT, Bauer M, Figge MT (2022) Spatial quantification of clinical biomarker pharmacokinetics through deep learning-based segmentation and signal-oriented analysis of MSOT data. Photoacoustics 26, 100361.
Press AT, Babic P, Hoffmann B, Müller T, Foo W, Hauswald W, Benecke J, Beretta M, Cseresnyés Z, Hoeppener S, Nischang I, Coldewey SM, Gräler MH, Bauer R, Gonnert F, Gaßler N, Wetzker R, Figge MT, Schubert US, Bauer M (2021) Targeted delivery of a phosphoinositide 3-kinase γ inhibitor to restore organ function in sepsis. EMBO Mol Med 13(10), e14436.
Böttcher B, Hoffmann B, Garbe E, Weise T, Cseresnyés Z, Brandt P, Dietrich S, Driesch D, Figge MT, Vylkova S (2020) The transcription factor Stp2 is important for Candida albicans biofilm establishment and sustainability. Front Microbiol 11, 794.
Kresinsky A, Schnöder TM, Jacobsen ID, Rauner M, Hofbauer LC, Ast V, König R, Hoffmann B, Svensson C-M, Figge MT, Hilger I, Heidel FH, Böhmer FD, Müller JP (2019) Lack of CD45 in FLT3-ITD mice results in a myeloproliferative phenotype, cortical porosity, and ectopic bone formation. Oncogene 38(24), 4773-4787.
Hermenau R, Ishida K, Gama S, Hoffmann B, Pfeifer-Leeg M, Plass W, Mohr JF, Wichard T, Saluz HP, Hertweck C (2018) Gramibactin is a bacterial siderophore with a diazeniumdiolate ligand system. Nat Chem Biol 14(9), 841-843.
Hoffmann B*, Svensson C-M*, Straßburger M, Gebser B, Irmler IM, Kamradt T, Saluz HP, Figge MT, *authors contributed equally (2017) Automated quantification of early bone alterations and pathological bone turnover in experimental arthritis by in vivo PET/CT imaging. Sci Rep 7, 2217.
Svensson C-M*, Hoffmann B*, Irmler I, Straßburger M, Figge MT**, Saluz HP**; *authors contributed equally; **corresponding authors, authors contributed equally (2017) Quantification of arthritic bone degradation by analysis of 3D micro-computed tomography data. Sci Rep 7, 44434.
Irmler IM, Gebhardt P, Hoffmann B, Opfermann T, Figge MT, Saluz HP, Kamradt T (2014) 18 F-Fluoride positron emission tomography/computed tomography for noninvasive in vivo quantification of pathophysiological bone metabolism in experimental murine arthritis. Arthritis Res Ther 16(4), R155.