
Sylvie McNamara (née Schulze)
Systembiologie und Bioinformatik Jetzt: Signature Diagnostics AG
Systems based modelling of human fungal pathogens interacting with the human immune system
- Modelling of host-pathogen interactions on a cellular level
- Interaction of human immune system cells and fungal pathogens
- Modelling of inter-species host-pathogen (gene regulatory) networks
(2020) Survival strategies of pathogenic Candida species in human blood show independent and specific adaptations. mBio 11(5), e02435-20. Details PubMed
(2017) LASSIM—A network inference toolbox for genome-wide mechanistic modeling. PLOS Comput Biol 13(6), e1005608. Details PubMed Open Access
(2016) Candida albicans infection leads to barrier breakdown and a MAPK/NF-κB mediated stress response in the intestinal epithelial cell line C2BBe1. Cellular Microbiology 18(7), 889-904. Details PubMed
(2016) How to Predict Molecular Interactions between Species? Front Microbiol 7, 442. Details PubMed
(2015) Data- and knowledge-based modeling of gene regulatory networks: An update EXCLI Journal - Experimental and Clinical Sciences 14, 346-378. Details PDF
(2015) Computational prediction of molecular pathogen-host interactions based on dual transcriptome data Front Microbiol 6, 65. Details PubMed Open Access