Curriculum vitae

Forschungsschwerpunkte
  • Molekulare Zusammenhänge zwischen Stoffwechsel und Virulenz bei pathogenen Candida spp.
  • Die Rolle von Stoffwechselsignalen bei der Etablierung mikrobieller Gemeinschaften
  • Infektionsmodelle der Candidose
Wissenschaftlicher Werdegang
seit 2016 NWG-Leiterin, NWG Host Fungal Interfaces, ZIK Septomics, Friedrich-Schiller-Universität Jena
2014-2016 Assistant Professor-Research, University of Texas Health Science Center at Houston, Houston, TX, USA
2012-2016 Adjunct Faculty, University of Houston-Downtown, Houston, TX, USA
2013-2014 Senior Research Associate, University of Texas Health Science Center at Houston, Houston, TX, USA
2007-2013 Post-doctoral fellow, University of Texas Health Science Center at Houston, Houston, TX, USA
2007 Ph.D., State University of New York at Buffalo, Buffalo, NY, USA
2006-2007 Wissenschaftliche Mitarbeiterin (PostDoc), Ottawa Health Research institute, Centre for Cancer Research, Ottawa, ON, Canada
2002-2006 Wissenschaftliche Mitarbeiterin, State University of New York at Buffalo, Department of Oral Biology, Buffalo, NY, USA
2004 M.Sc., State University of New York at Buffalo, Buffalo, NY, USA
2004 Wissenschaftliche Mitarbeiterin, State University of New York at Buffalo, Physiology Department Buffalo, NY, USA
2001 M.Sc., Sofia University, Sofia, Bulgaria
Auszeichnungen · Ämter · wissenschaftliche Aktivitäten
seit 2021 Editor, Microbiology Spectrum
seit 2018 Editor, Frontiers in Microbiology
2014 Judge Travel Grant, Annual Biomedical Research Conference for Minority Students, San Antonio, TX, USA
2014 ISHAM Young Fellow Travel Award, American society for Microbiology, 12th ASM Conference on Candida and Candidiasis, New Orleans, LA, USA
2011 Office of the Dean of McGovern Medical School Postdoctoral Fellow Travel Grant, University of Texas Health Science Center Houston, Houston, TX, USA

Publikationen

Vylkova S, Lorenz MC (2017) Phagosomal neutralization by the fungal pathogen Candida albicans induces macrophage pyroptosis. Infect Immun 85(2),
Danhof HA, Vylkova S, Vesely EM, Ford AE, Gonzalez-Garay M, Lorenz MC (2016) Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids. MBio 7(6),
Vylkova S, Lorenz MC (2014) Modulation of phagosomal pH by Candida albicans promotes hyphal morphogenesis and requires Stp2p, a regulator of amino acid transport. PLOS Pathog 10(3), e1003995.
Vylkova S, Carman AJ, Danhof HA, Collette JR, Zhou H, Lorenz MC (2011) The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH. MBio 2(3), e00055.
Miranda M, Bashi E, Vylkova S, Edgerton M, Slayman C, Rivetta A (2009) Conservation and dispersion of sequence and function in fungal TRK potassium transporters: focus on Candida albicans. FEMS Yeast Res 9(2), 278-292.
Carman AJ, Vylkova S, Lorenz MC (2008) Role of acetyl coenzyme A synthesis and breakdown in alternative carbon source utilization in Candida albicans. Eukaryot Cell 7(10), 1733-1741.
Vylkova S, Jang WS, Li W, Nayyar N, Edgerton M (2007) Histatin 5 initiates osmotic stress response in Candida albicans via activation of the Hog1 mitogen-activated protein kinase pathway. Eukaryot Cell 6(10), 1876-1888.
Vylkova S, Nayyar N, Li W, Edgerton M (2007) Human beta-defensins kill Candida albicans in an energy-dependent and salt-sensitive manner without causing membrane disruption. Antimicrob Agents Chemother 51(1), 154-161.
Vylkova S, Sun JN, Edgerton M (2007) The role of released ATP in killing Candida albicans and other extracellular microbial pathogens by cationic peptides. Purinergic Signal 3(1-2), 91-97.
Vylkova S, Li XS, Berner JC, Edgerton M (2006) Distinct antifungal mechanisms: beta-defensins require Candida albicans Ssa1 protein, while Trk1p mediates activity of cysteine-free cationic peptides. Antimicrob Agents Chemother 50(1), 324-331.

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