Slavena Vylkova

Dr. Slavena Vylkova

Host Fungal Interfaces · Leitung

Telefon: +49 3641 532-1473 E-Mail: Slavena.Vylkova@leibniz-hki.de

Publikationen

Böttcher B, Hoffmann B, Garbe E, Weise T, Cseresnyés Z, Brandt P, Dietrich S, Driesch D, Figge MT, Vylkova S (2020) The transcription factor Stp2 is important for Candida albicans biofilm establishment and sustainability. Front Microbiol 11, 794. Details PubMed Open Access PDF

Brandt P, Garbe E, Vylkova S (2020) Catch the wave: Metabolomic analyses in human pathogenic fungi. PLOS Pathog 16(8), e1008757. (Review) Details PubMed Open Access PDF

Gerwien F, Dunker C, Brandt P, Garbe E, Jacobsen ID, Vylkova S (2020) Clinical Candida albicans vaginal isolates and a laboratory strain show divergent behaviors during macrophage interactions. mSphere 5(4), e00393-20. Details PubMed Open Access PDF

Mirhakkak M, Schäuble S, Klassert T, Brunke S, Brandt P, Loos D, Uribe R, de Oliveira Lino FS, Ni Y, Vylkova S, Slevogt H, Hube B, Weiss G, Sommer M, Panagiotou G (2020) Metabolic modeling predicts specific gut bacteria as key determinants for Candida albicans colonization levels. ISME J [Epub ahead of print] Details PubMed Open Access

Ruben S, Garbe E, Mogavero S, Albrecht-Eckardt D, Hellwig D, Häder A, Krüger T, Gerth K, Jacobsen ID, Elshafee O, Brunke S, Hünniger K, Kniemeyer O, Brakhage AA, Morschhäuser J, Hube B, Vylkova S, Kurzai O, Martin R (2020) Ahr1 and Tup1 contribute to the transcriptional control of virulence-associated genes in Candida albicans. mBio 11(2), e00206-20. Details PubMed Open Access PDF

von Müller C, Bulman F, Wagner L, Rosenberger D, Marolda A, Kurzai O, Eißmann P, Jacobsen ID, Perner B, Hemmerich P, Vylkova S (2020) Active neutrophil responses counteract Candida albicans burn wound infection of ex vivo human skin explants. Sci Rep 10(1), 21818. Details PubMed Open Access PDF

Wagner L, Bloos F, Vylkova S (2020) Bloodstream infection due to Enterobacter ludwigii, correlating with massive aggregation on the surface of a central venous catheter. Infection 48(6), 955-958. Details PubMed Open Access

Weise T, Böttcher B, Vylkova S (2020) Bioflux analysis. Protocols , Details Open Access PDF

Garbe E, Vylkova S (2019) Role of amino acid metabolism in the virulence of human pathogenic fungi. Curr Clin Micro Rpt [Epub ahead of print] (Review) Details Open Access PDF

Vylkova S (2017) Environmental pH modulation by pathogenic fungi as a strategy to conquer the host. PLOS Pathog 13(2), e1006149. Details PubMed

Vylkova S, Lorenz MC (2017) Phagosomal neutralization by the fungal pathogen Candida albicans induces macrophage pyroptosis. Infect Immun 85(2), Details PubMed

Danhof HA, Vylkova S, Vesely EM, Ford AE, Gonzalez-Garay M, Lorenz MC (2016) Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids. MBio 7(6), Details PubMed

Vylkova S, Lorenz MC (2014) Modulation of phagosomal pH by Candida albicans promotes hyphal morphogenesis and requires Stp2p, a regulator of amino acid transport. PLOS Pathog 10(3), e1003995. Details PubMed

Vylkova S, Carman AJ, Danhof HA, Collette JR, Zhou H, Lorenz MC (2011) The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH. MBio 2(3), e00055. Details PubMed

Miranda M, Bashi E, Vylkova S, Edgerton M, Slayman C, Rivetta A (2009) Conservation and dispersion of sequence and function in fungal TRK potassium transporters: focus on Candida albicans. FEMS Yeast Res 9(2), 278-292. Details PubMed

Carman AJ, Vylkova S, Lorenz MC (2008) Role of acetyl coenzyme A synthesis and breakdown in alternative carbon source utilization in Candida albicans. Eukaryot Cell 7(10), 1733-1741. Details PubMed

Vylkova S, Jang WS, Li W, Nayyar N, Edgerton M (2007) Histatin 5 initiates osmotic stress response in Candida albicans via activation of the Hog1 mitogen-activated protein kinase pathway. Eukaryot Cell 6(10), 1876-1888. Details PubMed

Vylkova S, Nayyar N, Li W, Edgerton M (2007) Human beta-defensins kill Candida albicans in an energy-dependent and salt-sensitive manner without causing membrane disruption. Antimicrob Agents Chemother 51(1), 154-161. Details PubMed

Vylkova S, Sun JN, Edgerton M (2007) The role of released ATP in killing Candida albicans and other extracellular microbial pathogens by cationic peptides. Purinergic Signal 3(1-2), 91-97. Details PubMed

Vylkova S, Li XS, Berner JC, Edgerton M (2006) Distinct antifungal mechanisms: beta-defensins require Candida albicans Ssa1 protein, while Trk1p mediates activity of cysteine-free cationic peptides. Antimicrob Agents Chemother 50(1), 324-331. Details PubMed

Baev D, Rivetta A, Vylkova S, Sun JN, Zeng GF, Slayman CL, Edgerton M (2004) The TRK1 potassium transporter is the critical effector for killing of Candida albicans by the cationic protein, Histatin 5. J Biol Chem 279(53), 55060-55072. Details PubMed

Baev D, Rivetta A, Li XS, Vylkova S, Bashi E, Slayman CL, Edgerton M (2003) Killing of Candida albicans by human salivary histatin 5 is modulated, but not determined, by the potassium channel TOK1. Infect Immun 71(6), 3251-3260. Details PubMed

Dong J, Vylkova S, Li XS, Edgerton M (2003) Calcium blocks fungicidal activity of human salivary histatin 5 through disruption of binding with Candida albicans. J Dent Res 82(9), 748-752. Details PubMed