(2023)
High-throughput profiling of Candida auris isolates reveals clade-specific metabolic differences.
Microbiol Spectr 11(3),
e0049823.
(Review)
Dr. Slavena Vylkova
Host Fungal Interfaces · Leitung +49 3641 532-1473 Slavena.Vylkova@leibniz-hki.deCurriculum vitae
Forschungsschwerpunkte
- Molekulare Zusammenhänge zwischen Stoffwechsel und Virulenz bei pathogenen Candida spp.
- Die Rolle von Stoffwechselsignalen bei der Etablierung mikrobieller Gemeinschaften
- Infektionsmodelle der Candidose
Wissenschaftlicher Werdegang
| seit 2016 | NWG-Leiterin, NWG Host Fungal Interfaces, ZIK Septomics, Friedrich-Schiller-Universität Jena |
| 2014-2016 | Assistant Professor-Research, University of Texas Health Science Center at Houston, Houston, TX, USA |
| 2012-2016 | Adjunct Faculty, University of Houston-Downtown, Houston, TX, USA |
| 2013-2014 | Senior Research Associate, University of Texas Health Science Center at Houston, Houston, TX, USA |
| 2007-2013 | Post-doctoral fellow, University of Texas Health Science Center at Houston, Houston, TX, USA |
| 2007 | Ph.D., State University of New York at Buffalo, Buffalo, NY, USA |
| 2006-2007 | Wissenschaftliche Mitarbeiterin (PostDoc), Ottawa Health Research institute, Centre for Cancer Research, Ottawa, ON, Canada |
| 2002-2006 | Wissenschaftliche Mitarbeiterin, State University of New York at Buffalo, Department of Oral Biology, Buffalo, NY, USA |
| 2004 | M.Sc., State University of New York at Buffalo, Buffalo, NY, USA |
| 2004 | Wissenschaftliche Mitarbeiterin, State University of New York at Buffalo, Physiology Department Buffalo, NY, USA |
| 2001 | M.Sc., Sofia University, Sofia, Bulgaria |
Auszeichnungen · Ämter · wissenschaftliche Aktivitäten
| seit 2021 | Editor, Microbiology Spectrum |
| seit 2018 | Editor, Frontiers in Microbiology |
| 2014 | Judge Travel Grant, Annual Biomedical Research Conference for Minority Students, San Antonio, TX, USA |
| 2014 | ISHAM Young Fellow Travel Award, American society for Microbiology, 12th ASM Conference on Candida and Candidiasis, New Orleans, LA, USA |
| 2011 | Office of the Dean of McGovern Medical School Postdoctoral Fellow Travel Grant, University of Texas Health Science Center Houston, Houston, TX, USA |
Publikationen
(2023)
Functional analysis of the Candida albicans ECE1 Promoter.
Microbiol Spectr 11(2),
e0025323.
(2023)
Pathogen-specific innate immune response patterns are distinctly affected by genetic diversity.
Nat Commun 14(1),
3239.
(2023)
Escherichia coli nissle 1917 antagonizes Candida albicans growth and protects intestinal cells from C. albicans-mediated damage.
Microorganisms 11(8),
1929.
(2022)
Lactobacillus rhamnosus colonisation antagonizes Candida albicans by forcing metabolic adaptations that compromise pathogenicity.
Nat Commun 13(1),
3192.
(2022)
Impaired amino acid uptake leads to global metabolic imbalance of Candida albicans biofilms.
NPJ Biofilms Microbiomes 8(1),
78.
(2022)
Candida albicans SR-like protein kinases regulate different cellular processes: Sky1 is involved in control of ion homeostasis, while Sky2 is important for dipeptide utilization.
Front Cell Infect Microbiol 12,
850531.
(2022)
Systematic metabolic profiling identifies de novo sphingolipid synthesis as hypha associated and essential for Candida albicans filamentation.
mSystems 7(6),
e0053922.
(2022)
GNP2 encodes a high-specificity proline permease in Candida albicans.
mBio 13(1),
e0314221.
(2021)
Metabolic modeling predicts specific gut bacteria as key determinants for Candida albicans colonization levels.
ISME J 15(5),
1257-1270.
