Segmentation of cell structures using Model-Based Set Covering with iterative reweighting

Markowsky P, Reith S, Zuber TE, König R, Rohr K, Schnörr C (2017) Segmentation of cell structures using Model-Based Set Covering with iterative reweighting In: IEEE International Symposium on Biomedical Imaging, Melbourne, Australia, 04/18/2017-04/21/2017, pp. 392-396.IEEE. ISBN: 1945-8452.

Abstract

We present a new method for cell segmentation which combines a marked point process model with a combinatorics-based method of finding global optima. The method employs an energy term that assesses possible segmentations by their fidelity to both local image information and a simple model of cell interaction, and we use a randomized iterative reweighting technique for its minimization. Our approach was successfully applied to cell microscopy images of varying difficulty and experimentally compared with both a standard segmentation method as well as a method based on Multiple Birth and cut. The proposed method is found to improve upon previous approaches.

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Identifier

doi: 10.1109/ISBI.2017.7950545