Teresa Lehnert

Dr. Teresa Lehnert

Angewandte Systembiologie · CSCC

Telefon: +49 3641 532-1409 Telefax: +49 3641 532-2409 E-Mail: teresa.lehnert@leibniz-hki.de

Forschungsschwerpunkte
  • Computersimulation von virtuellen Infektionsmodellen
  • populationsbasierte, zustandsbasierte und agentenbasierte Modellierung
  • Anwendung globaler Optimierungsalgorithmen zur Schätzung von unbekannten Modellparametern
Themenfelder
Curriculum vitae

Wissenschaftlicher Werdegang

seit 2016 Wissenschaftliche Mitarbeiterin in der Gruppe Angewandte Systembiology am Hans-Knöll-Institut
2017 Dr. rer. nat. in Bioinformatik an der Friedrich-Schiller-Universität Jena
2011 Diplom in Bioinformatik an der Friedrich-Schiller-Universität Jena
Publikationen

Sreekantapuram S*, Lehnert T*, Prauße MT, Berndt A, Berens C, Figge MT**, Jacobsen ID**; *authors contributed equally; *corresponding authors; **authors contributed equally (2020) Dynamic interplay of host and pathogens in an avian whole blood model. Frontiers in Immunology 11, 500. Details PubMed Open Access PDF Supplement

Prauße MTE, Lehnert T, Timme S, Hünniger K, Leonhardt I, Kurzai O, Figge MT (2018) Predictive virtual infection modeling of fungal immune evasion in human whole blood. Frontiers in Immunology 9, 560. Details PubMed Open Access PDF Supplement

Timme S, Lehnert T, Prauße MTE, Hünniger K, Leonhardt I, Kurzai O, Figge MT (2018) Quantitative simulations predict treatment strategies against fungal infections in virtual neutropenic patients. Frontiers in Immunology 9, 667. Details PubMed Open Access PDF Supplement

Lehnert T, Figge MT (2017) Dimensionality of motion and binding valency govern receptor-ligand kinetics as revealed by agent-based modeling. Front Immunol 8, 1692. Details PubMed Open Access PDF Supplement

Duggan S, Essig F, Hünniger K, Mokhtari Z, Bauer L, Lehnert T, Brandes S, Häder A, Jacobsen ID, Martin R, Figge MT, Kurzai O (2015) Neutrophil activation by Candida glabrata but not Candida albicans promotes fungal uptake by monocytes. Cell Microbiol 17(9), 1259-1276. Details PubMed

Hünniger K, Bieber K, Martin R, Lehnert T, Figge MT, Löffler J, Guo R, Riedemann N, Kurzai O (2015) A second stimulus required for enhanced antifungal activity of human neutrophils in blood is provided by anaphylatoxin C5a. The Journal of Immunology 194(3), 1199-1210. Details PubMed

Lehnert T*, Timme S*, Pollmächer J, Hünniger K, Kurzai O, Figge MT (2015) Bottom-up modeling approach for the quantitative estimation of parameters in pathogen-host interactions. Frontiers in Microbiology 6(608), *authors contributed equally. Details PubMed Open Access

Hünniger K*, Lehnert T*, Bieber K, Martin R, Figge MT⁺, Kurzai O⁺ (2014) A virtual infection model quantifies innate effector mechanisms and Candida albicans immune escape in human blood. PLOS Comput Biol 10(2), e1003479, */⁺authors contributed equally. Details PubMed Open Access

Mech F, Wilson D, Lehnert T, Hube B, Figge MT (2014) Epithelial invasion outcompetes hypha development during Candida albicans infection as revealed by an image-based systems biology approach. Cytometry A 85(2), 126-139. Details PubMed

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