Abstract
The detailed structure of brain-derived Aβ amyloid fibrils is unknown. To approach this issue, we investigate the molecular architecture of Aβ(1-40) fibrils grown in either human cerebrospinal fluid solution, in chemically simple phosphate buffer in vitro or extracted from a cell culture model of Aβ amyloid plaque formation.
Beteiligte Forschungseinheiten
Themenfelder
Identifier
doi: 10.3109/13506129.2016.1146989
PMID: 26972581