Curriculum vitae

Wissenschaftlicher Werdegang
2016 -today Junior Group Leader
2014 - 2016 PostDoc (Feodor Lynen Research Fellowship)
ETH Zurich (Jörn Piel)
Research focus: Genomics of uncultured natural product producers, biosynthesis of ribosomally produced small molecules
2011 - 2014 PostDoc
FSU Jena (Dirk Hoffmeister)
Research focus: Polyketide and nonribosomal peptide biosynthesis in mushrooms.
2006 - 2011 PhD student
HKI Jena (Christian Hertweck)
Research focus: Genomics of natural product-producing bacterial endosymbionts of fungi.
2001 - 2006 Studies of Biochemistry
FSU, Jena

Publikationen

Braga D, Last D, Hasan M, Guo H, Leichnitz D, Uzum Z, Richter I, Schalk F, Beemelmanns C, Hertweck C, Lackner G (2019) Metabolic pathway rerouting in Paraburkholderia rhizoxinica evolved long-overlooked derivatives of coenzyme F420. ACS Chem Biol 14(9), 2088-2094.
Götze S, Arp J, Lackner G, Zhang S, Kries H, Klapper M, García-Altares M, Willing K, Günther M, Stallforth P (2019) Structure elucidation of the syringafactin lipopeptides provides insight in the evolution of nonribosomal peptide synthetases. Chem Sci 10(48), 10979-10990.
Stöckli M, Morinaka BI, Lackner G, Kombrink A, Sieber R, Margot C, Stanley CE, deMello AJ, Piel J, Künzler M (2019) Bacteria-induced production of the antibacterial sesquiterpene lagopodin B in Coprinopsis cinerea. Mol Microbiol 112(2), 605-619.
Brandenburger E, Braga D, Kombrink A, Lackner G, Gressler J, Künzler M, Hoffmeister D (2018) Multi-genome analysis identifies functional and phylogenetic diversity of basidiomycete adenylate-forming reductases. Fungal Genet Biol 112, 55-63.
Guo H, Schmidt A, Stephan P, Raguž L, Braga D, Kaiser M, Dahse HM, Weigel C, Lackner G, Beemelmanns C (2018) Precursor-directed diversification of cyclic tetrapeptidic pseudoxylallemycins. ChemBioChem 19(21), 2307-2311.
Klapper M, Braga D, Lackner G, Herbst R, Stallforth P (2018) Bacterial alkaloid biosynthesis: Structural diversity via a minimalistic nonribosomal peptide synthetase. Cell Chem Biol 25(6), 659-665.
Braga D, Lackner G (2017) One ring to fight them all: The sulfazecin story. Cell Chem Biol 24(1), 1-2. (Review)
Brandenburger E, Gressler M, Leonhardt R, Lackner G, Habel A, Hertweck C, Brock M, Hoffmeister D (2017) A highly conserved basidiomycete peptide synthetase produces a trimeric hydroxamate siderophore. Appl Environ Microbiol 83(21), e01478.
Lackner G, Peters EE, Helfrich EJN, Piel J (2017) Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges. Proc Natl Acad Sci U S A 114(3), E347-E356.
Fuchs S W, Lackner G, Morinaka B I, Morishita Y, Asai T, Riniker S, Piel J (2016) A Lanthipeptide-like N-Terminal Leader Region Guides Peptide Epimerization by Radical SAM Epimerases: Implications for RiPP Evolution Angew Chem Int Ed Engl 55(40), 12330-12333.