Dr. Olaf Kniemeyer
Telefon: +49 3641 532-1071 Telefax: +49 3641 532-2071 E-Mail: email@example.com
(2021) Carbon catabolite repression in filamentous fungi is regulated by phosphorylation of the transcription factor CreA. mBio 12(1), e03146-20.
(2021) Serological proteome analysis for the characterization of secreted fungal protein antigens. In: Methods Mol Biol 2260, pp. 15-26. Springer.
(2021) Discovery of fungal surface NADases predominantly present in pathogenic species. Nat Commun 12(1), 1631.
(2020) Dynamic surface proteomes of allergenic fungal conidia. J Proteome Res 19(5), 2092-2104.
(2020) Immune modulation by complement receptor 3-dependent human monocyte TGF-ß1-transporting vesicles. Nat Commun 11(1), 2331.
(2020) Functional surface proteomic profiling reveals the host heat-shock protein A8 as a mediator of Lichtheimia corymbifera recognition by murine alveolar macrophages. Environ Microbiol 22(9), 3722-3740.
(2020) Biotinylated surfome profiling identifies potential biomarkers for diagnosis and therapy of Aspergillus fumigatus infection. mSphere 5(4), e00535-20.
(2020) Identification of PARP-1, histone H1 and SIRT-1 as new regulators of breastcancer-related aromatase promoter I.3/II. Cells 9(2), 427.
(2020) Ahr1 and Tup1 contribute to the transcriptional control of virulence-associated genes in Candida albicans. mBio 11(2), e00206-20.
(2020) The domestic pig as human-relevant large animal model to studyadaptive antifungal immune responses against airborne Aspergillus fumigatus. EurJ Immunol 50(11), 1712-1728.
(2020) Human neutrophils produce antifungal extracellular vesicles against Aspergillus fumigatus. mBio 11(2), e00596-20.
(2020) The role of RodA-conserved cysteine residues in the Aspergillus fumigatus conidial surface organization. J Fungi 6(3), E151.
(2019) Human anti-fungal Th17 immunity and pathology rely on cross-reactivity against Candida albicans. Cell 176(6), 1340-1355.
(2019) Conidial surface proteins at the interface of fungal infections. PLOS Pathog 15(9), e1007939. (Review)
(2019) The monothiol glutaredoxin GrxD is essential for sensing iron starvation in Aspergillus fumigatus. PLOS Genetics 15(9), e1008379.
(2019) Crosstalk between Ras and inositol phosphate signaling revealed by lithium action on inositol monophosphatase in Schizophyllum commune. Adv Biol Regul 72, 78-88.
(2019) Stress-induced changes in the lipid microenvironment of β-(1,3)-d-glucan synthase cause clinically important Echinocandin resistance in Aspergillus fumigatus. mBio 10(3), e00779-19.
(2019) Redox proteomic analysis reveals oxidative modifications of proteins by increased levels of intracellular reactive oxygen species during hypoxia adaptation of Aspergillus fumigatus. Proteomics 19(5), e1800339.
(2018) ATP content and cell viability as indicators for cryostress across the diversity of life. Front Physiol 9, 921.
(2018) Module-detection approaches for the integration of multilevel omics data highlight the comprehensive response of Aspergillus fumigatus to caspofungin. BMC Syst Biol 12(1), 88.
(2018) Identification of proteomic markers in head and neck cancer using MALDI-MS imaging, LC-MS/MS, and immunohistochemistry. Proteomics Clin Appl 31(1), e1700173.
(2018) Additional oxidative stress reroutes the global response of Aspergillus fumigatus to iron depletion. BMC Genomics 19(1), 357.
(2018) Processing of Candida albicans Ece1p is critical for Candidalysin maturation and fungal virulence. mBio 9(1), e02178-17.
(2018) Proteomics of Aspergillus fumigatus conidia-containing phagolysosomes identifies processes governing immune evasion. Mol Cell Proteomics 17(6), 1084-1096.
(2018) Arabidopsis thaliana responds to colonisation of Piriformospora indica by secretion of symbiosis-specific proteins. PLOS One 13(12), e0209658.
(2018) Proteomic differences between azole-susceptible and -resistant Aspergillus fumigatus strains. Adv Microbiol 8(1), 77-99.
(2018) Proteome analysis reveals the conidial surface protein CcpA essential for virulence of the pathogenic fungus Aspergillus fumigatus. mBio 9(5), e01557-18.
(2018) The regulator of G-protein signalling Thn1 links pheromone response to volatile production in Schizophyllum commune. Environ Microbiol 20(10), 3684-3699.
(2018) UV-Raman spectroscopic identification of fungal spores important for respiratory diseases. Anal Chem 90(15), 8912-8918.
(2017) Proteomic profiling of the antifungal drug response of Aspergillus fumigatus to voriconazole. Int J Med Microbiol 307(7), 398-408.
(2017) Lipid signaling via Pkh1/2 regulates fungal CO2 sensing through the kinase Sch9. mBio 8(1), e02211-16.
(2017) Quantitative Analysis of Proteome Modulations in Alveolar Epithelial Type II Cells in Response to Pulmonary Aspergillus fumigatus Infection. Mol Cell Proteomics 16(12), 2184-2198.
(2017) Induction of Mitochondrial Reactive Oxygen Species Production by Itraconazole, Terbinafine, and Amphotericin B as a Mode of Action against Aspergillus fumigatus. Antimicrob Agents Chemother 61(11), e00978-17.
(2017) Phenotypic and Proteomic Analysis of the Aspergillus fumigatus ΔPrtT, ΔXprG and ΔXprG/ΔPrtT Protease-Deficient Mutants. Front Microbiol 8, 2490.
(2017) Identification of Proteins Interacting with Cytoplasmic High-Mobility Group Box 1 during the Hepatocellular Response to Ischemia Reperfusion Injury. Int J Mol Sci 18(1), pii: E167.
(2016) Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans. Cell 167(4), 1067-1078.e16.
(2016) Smelling the difference: Transcriptome, proteome and volatilome changes after mating. Fungal Genet Biol 112, 2-11.
(2016) Immunoproteomics of Aspergillus for the development of biomarkers and immunotherapies. Proteomics Clin Appl 10(9-10), 910-921. (Review)
(2016) The transcriptional regulators SteA and StuA contribute to keratin degradation and sexual reproduction of the dermatophyte Arthroderma benhamiae. Curr Genet 63(1), 103-116.
(2016) HapX Mediates Iron Homeostasis in the Pathogenic Dermatophyte Arthroderma benhamiae but Is Dispensable for Virulence. PLOS ONE 11(3), e0150701.
(2016) The hypoxia-induced dehydrogenase HorA is required for coenzyme Q10 biosynthesis, azole sensitivity and virulence of Aspergillus fumigatus Mol Microbiol 101(1), 92-108.
(2016) Immunoproteomic analysis of antibody responses to extracellular proteins of Candida albicans revealed the importance of glycosylation for antigen recognition. J Proteome Res 15(8), 2394-2406.
(2016) Candidalysin is a fungal peptide toxin critical for mucosal infection. Nature 532(7597), 64-68.
(2016) Proteomic profiling of serological responses to Aspergillus fumigatus antigens in patients with invasive aspergillosis. J Proteome Res 15(5), 1580-1591.
(2016) Identification and characterization of a novel Aspergillus fumigatus rhomboid family putative protease RbdA involved in hypoxia sensing and virulence. Infect Immun 84(6), 1866-1878.
(2015) Network Modeling Reveals Cross Talk of MAP Kinases during Adaptation to Caspofungin Stress in Aspergillus fumigatus. PLOS One 10(9), e0136932.
(2015) Clinical-scale isolation of the total Aspergillus fumigatus-reactive T-helper cell repertoire for adoptive transfer. Cytotherapy 17(10), 1396-1405.
(2015) Fungus-specific CD4(+) T cells for rapid identification of invasive pulmonary mold infection. Am J Respir Crit Care Med 191(3), 348-352.
(2015) Comparative proteomics of a tor inducible Aspergillus fumigatus mutant reveals involvement of the Tor kinase in iron regulation. Proteomics 15(13), 2230-2243.
(2015) Interference of Aspergillus fumigatus with the immune response. Semin Immunopathol 37(2), 141-152. (Review)
(2015) Insights into the cellular responses to hypoxia in filamentous fungi. Curr Genet 61(3), 441-455.
(2015) Challenges and Strategies for Proteome Analysis of the Interaction of Human Pathogenic Fungi with Host Immune Cells. Proteomes 3(4), 467-495. (Review)
(2015) A phosphorylation code of the Aspergillus nidulans global regulator VelvetA (VeA) determines specific functions. Mol Microbiol 99(5), 909-924.
(2015) Hitting the caspofungin salvage pathway of human-pathogenic fungi with the novel lasso peptide humidimycin (MDN-0010). Antimicrob Agents Chemother 59(9), 5145-5153.
(2015) Influence of zygomycete-derived D'orenone on IAA signaling in Tricholoma-spruce ectomycorrhiza. Environ Microbiol 18(8), 2470-2480.
(2015) Tricholoma vaccinum host communication during ectomycorrhiza formation. FEMS Microbiol Ecol 91(11),
(2014) Antigen-specific expansion of human regulatory T cells as a major tolerance mechanism against mucosal fungi. Mucosal Immunol 7(4), 916-928.
(2014) Identification of immunogenic antigens from Aspergillus fumigatus by direct multi-parameter characterization of specific conventional and regulatory CD4+ T cells. Journal of Immunology 197(7), 3332-3343.
(2014) Surface structure characterization of Aspergillus fumigatus conidia mutated in the melanin synthesis pathway and their human cellular immune response. Infect Immun 82(8), 3141-3153.
(2014) The novel globin protein fungoglobin is involved in low oxygen adaptation of Aspergillus fumigatus. Mol Microbiol 93(3), 539-553.
(2014) Identification of hypoxia-inducible target genes of Aspergillus fumigatus by transcriptome analysis reveals cellular respiration as important contributor to hypoxic survival. Eukaryot Cell 13(9), 1241-1253.
(2014) Characterisation of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and impact on virulence. Frontiers in Microbiology 5, 469.
(2014) Urine protein profiling identified alpha-1-microglobulin and haptoglobin as biomarkers for early diagnosis of acute allograft rejection following kidney transplantation. World J Urol 32(6), 1619-1624.
(2013) Deletion of the α-(1,3)-glucan synthase genes induces a restructuring of the conidial cell wall responsible for the avirulence of Aspergillus fumigatus. PLOS Pathog 9(11), e1003716.
(2013) Investigation of Aspergillus fumigatus biofilm formation by various Front Microbiol 4, 13-13.
(2013) Extrinsic extracellular DNA leads to biofilm formation and colocalizes with matrix polysaccharides in the human pathogenic fungus Aspergillus fumigatus. Front Microbiol 4, 141.
(2012) Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter. BMC Genomics 13, 62-62.
(2012) The Arthroderma benhamiae hydrophobin HypA mediates hydrophobicity and influences recognition by human immune effector cells. Eukaryot Cell 11(5), 673-682.
(2012) Systems biology of fungal infection. Front Microbiol 3, 108.
(2012) Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus reveals novel insights into the genome and MpkA dependent gene expression. BMC Genomics 13, 519.
(2012) Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans - The role of a putative dehydrin. J Proteomics 75(13), 4038-4049.
(2011) On the way toward systems biology of Aspergillus fumigatus infection. Int J Med Microbiol 301(5), 453-459.
(2011) Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi. Genome Biol 12(1), R7.
(2011) Proteomics of eukaryotic microorganisms: The medically and biotechnologically important fungal genus Aspergillus. Proteomics 11(15), 3232-3243.
(2011) Identification of virulence determinants of the human pathogenic fungi Aspergillus fumigatus and Candida albicans by proteomics. Int J Med Microbiol 301(5), 368-377.
(2011) Analysis of the Aspergillus fumigatus proteome reveals metabolic changes and the activation of the pseurotin A biosynthesis gene cluster in response to hypoxia. J Proteome Res 10(5), 2508-2524.
(2011) Secretome analysis of Aspergillus fumigatus reveals Asp-hemolysin as a major secreted protein. Int J Med Microbiol 301(7), 602-611.
(2010) Integrative analysis of the heat shock response in Aspergillus fumigatus. BMC Genomics 11, 32.
(2010) Missing values in gel-based proteomics. Proteomics 10(6), 1202-1211.
(2010) Production of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodA. PLOS Pathog 6(4), e1000873.
(2010) Functional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin. Proteomics 10(17), 3097-3107.
(2010) Members of protein O-mannosyltransferase family in Aspergillus fumigatus differentially affect growth, morphogenesis and viability. Mol Microbiol 76(5), 1205-1221.
(2010) Proteome profiling and functional classification of intracellular proteins from conidia of the human-pathogenic mold Aspergillus fumigatus. J Proteome Res 9(7), 3427-3442.
(2009) Surface hydrophobin prevents immune recognition of airborne fungal spores. Nature 460(7259), 1117-1121.
(2009) Proteome analysis for pathogenicity and new diagnostic markers for Aspergillus fumigatus. Med Mycol 47 Suppl 1, S248-S254.
(2009) Production of pyomelanin, a second type of melanin, via the tyrosine degradation pathway in Aspergillus fumigatus. Appl Environ Microbiol 75(2), 493-503.
(2009) Two-dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus. Proteomics 9(5), 1407-1415.
(2008) Protein kinase A regulates growth, sporulation, and pigment formation in Aspergillus fumigatus. Appl Environ Microbiol 74(15), 4923-4933.
(2007) Discovery of gene regulatory networks in Aspergillus fumigatus Lect Notes Bioinf 4366,
(2007) Interaction of HapX with the CCAAT-binding complex--a novel mechanism of gene regulation by iron. EMBO J 26(13), 3157-3168.
(2007) The Aspergillus fumigatus transcriptional regulator AfYap1 represents the major regulator for defense against reactive oxygen intermediates but is dispensable for pathogenicity in an intranasal mouse infection model. Eukaryot Cell 6(12), 2290-2302.
(2006) Optimisation of a 2-D gel electrophoresis protocol for the human-pathogenic fungus Aspergillus fumigatus. Curr Genet 49(3), 178-189.