(2025)
Dual-use virulence factors of the opportunistic pathogen Chromobacterium haemolyticum mediate haemolysis and colonization.
bioRxiv
[Preprint]
Dr. Felix Trottmann
AlumniPublikationen
(2024)
The fatal mushroom neurotoxin muscarine is released from a harmless phosphorylated precursor upon cellular injury.
Angew Chem Int Ed 63(52),
e202417220.
(2024)
A catch-release strategy for the genomics-driven discovery of antiproliferative furan-functionalized peptides.
Angew Chem Int Ed ,
e202421760.
(2024)
Direct a-hydroxy acid loading onto a bacterial thiotemplate assembly line via a multienzyme gateway.
Angew Chem Int Ed 63(30),
e202405165.
(2024)
Novel biocatalysts from specialized metabolism.
Angew Chem Int Ed 63(4),
e202309284.
(Review)
(2024)
Analysis of the valgamicin biosynthetic pathway reveals a general mechanism for cyclopropanol formation across diverse natural product scaffolds.
ACS Chem Biol 19(3),
660-668.
(2023)
A "Magic Mushroom" multi-product sesquiterpene synthase.
ChemBioChem 24(21),
e202300511.
(2023)
Bacterial pathogen channels medium-sized fatty acids into malleicyprol biosynthesis.
ACS Chem Biol 18(7),
1557-1563.
(2022)
Assessment of bioactivity-modulating pseudo-ring formation in psilocin and related tryptamines.
ChemBioChem 23(13),
e202200183.
(2022)
An intramodular thioesterase domain catalyses chain release in the biosynthesis of a cytotoxic virulence factor.
RSC Chem Biol 3(9),
1121-1128.