(2024)
Bacteria from the Amycolatopsis genus associated with a toxic bird secrete protective secondary metabolites.
Nat Commun 15(1),
8524.
Elena Seibel
Chemische Biologie der Mikroben-Wirt Interaktionen · Doktorandin +49 3641 532-1226 elena.seibel@leibniz-hki.deCurriculum vitae
Forschungsschwerpunkte
- Aufklärung von Biosynthesewegen mikrobieller Sekundärmetabolite
- Identifizierung chemischer Mediatoren in komplexen mikrobiellen Systemen
Wissenschaftlicher Werdegang
| seit 2018 | Doktorandin (ANR-Projekt: „BiBiMac - Biomimetic synthesis, biosynthetic pathway engineering and structure studies of unique glycosylated macrolactams”) |
| 2013 – 2017 | M. Sc. Chemische Biologie, FSU Jena |
| 2015 | Erasmussemester, Faculdade de Ciências da Universidade de Lisboa |
| 2010 – 2013 | B. Sc. Biochemie/ Molekularbiologie, Fakultät der Biowissenschaften, FSU Jena |
Auszeichnungen · Ämter · wissenschaftliche Aktivitäten
| 2016 | Forschungspraktikum am D. K. Zabolotny Institut für Mikrobiologie und Virologie Kiew, Ukraine |
| 2015 | Forschungspraktikum in Hovione FarmaCiência S.A., Sete Casas, Loures, Portugal |
| 2014 | Forschungspraktikum am Instiut für Biologie und Zootechnik, Universidade Paulista, Câmpus Ilha Solteira |
| 2012 - 2014 |
studentische Hilfskraft am Max-Planck-Institut für Chemische Ökologie (MPI-CE), Jena |
| 2011 - 2013 |
Tutorin am Lehrstuhl für Ökologie, Fakultät der Biowissenschaften, FSU Jena |
Publikationen
(2023)
Adaptations of Pseudoxylaria towards a comb-associated lifestyle in fungus-farming termite colonies.
ISME J 17(5),
733-747.
(2023)
Genome mining for macrolactam-encoding gene clusters allowed for the network-guided isolation of β-amino acid-containing cyclic derivatives and heterologous production of ciromicin A.
Commun Chem 6(1),
257.
(2022)
Insights into the metabolomic capacity of Podaxis and isolation of podaxisterols A-D, ergosterol derivatives carrying nitrosyl cyanide-derived modifications.
J Nat Prod 85(9),
2159-2167.
(2022)
Comparative genomic and metabolomic analysis of Termitomyces species provides insights into the terpenome of the fungal cultivar and the characteristic odor of the fungus garden of Macrotermes natalensis termites.
mSystems 7(1),
e0121421.
(2021)
Identification of a sulfatase that detoxifies glucosinolates in the phloem-feeding insect Bemisia tabaci and prefers indolic glucosinolates.
Front Plant Sci 12,
671286.
(2021)
Female-biased sex allocation and lack of inbreeding avoidance in Cubitermes termites.
Ecol Evol 11(10),
5598-5605.
(2021)
Targeted isolation of saalfelduracin B-D from Amycolatopsis saalfeldensis using LC-MS/MS-based molecular networking.
J Nat Prod 84(4),
1002-1011.
(2020)
Stereoselective construction of (E,Z)-1,3-dienes and its application in natural product synthesis.
Adv Synth Catal 362(24),
5532-5575.
(Review)
(2020)
The fall armyworm Spodoptera frugiperda utilizes specific UDP-Glycosyltransferases to inactivate maize defensive benzoxazinoids.
Front Physiol 11,
604754.