Publikationen

Manfiolli AO, Siqueira FS, Dos Reis TF, Van Dijck P, Schrevens S, Hoefgen S, Föge M, Straßburger M, de Assis LJ, Heinekamp T, Rocha MC, Janevska S, Brakhage AA, Malavazi I, Goldman GH, Valiante V (2019) Mitogen-activated protein kinase cross-talk interaction modulates the production of melanins in Aspergillus fumigatus. mBio 10(2), e00215-19.
Zhao C, Fraczek M, Dineen L, Lebedinec R, Macheleidt J, Heinekamp T, Delneri D, Bowyer P, Brakhage AA, Bromley M (2019) High throughput gene replacement in Aspergillus fumigatus. Curr Protoc Microbiol 54(1), e88.
Bakti F, Sasse C, Heinekamp T, Pócsi I, Braus GH (2018) Heavy metal-induced expression of PcaA provides cadmium tolerance to Aspergillus fumigatus and supports its virulence in the Galleria mellonella model. Front Microbiol 9, 744.
Long N, Orasch T, Zhang S, Gao L, Xu X, Hortschansky P, Ye J, Zhang F, Xu K, Gsaller F, Straßburger M, Binder U, Heinekamp T, Brakhage AA, Haas H, Lu L (2018) The Zn2Cys6-type transcription factor LeuB cross-links regulation of leucine biosynthesis and iron acquisition in Aspergillus fumigatus. PLOS Genet 14(10), e1007762.
Scharf DH, Dworschak JD, Chankhamjon P, Scherlach K, Heinekamp T, Brakhage AA, Hertweck C (2018) Reconstitution of enzymatic carbon-sulfur bond formation reveals detoxification-like strategy in fungal toxin biosynthesis. ACS Chem Biol 13(9), 2508-2512.
Schmidt H, Vlaic S, Krüger T, Schmidt F, Balkenhohl J, Dandekar T, Guthke R, Kniemeyer O, Heinekamp T, Brakhage AA (2018) Proteomics of Aspergillus fumigatus conidia-containing phagolysosomes identifies processes governing immune evasion. Mol Cell Proteomics 17(6), 1084-1096.
Voltersen V, Blango MG, Herrmann S, Schmidt F, Heinekamp T, Strassburger M, Krüger T, Bacher P, Lother J, Weiss E, Hünniger K, Liu H, Hortschansky P, Scheffold A, Loeffler J, Krappmann S, Nietzsche S, Kurzai O, Einsele H, Kniemeyer O, Filler S, Reichard U, Brakhage AA (2018) Proteome analysis reveals the conidial surface protein CcpA essential for virulence of the pathogenic fungus Aspergillus fumigatus. mBio 9(5), e01557-18.
Johns A†, Scharf DH†, Gsaller F, Schmidt H, Heinekamp T, Straßburger M, Oliver JD, Birch M, Beckmann N, Dobb KS, Gilsenan J, Rash B, Bignell E, Brakhage AA*, Bromley MJ* †shared first authors, *corresponding authors (2017) A nonredundant phosphopantetheinyl transferase, PptA, is a novel antifungal target that directs secondary metabolite, siderophore, and lysine biosynthesis in Aspergillus fumigatus and is critical for pathogenicity. MBio 8(4), e01504-e01516.
Hillmann F, Bagramyan K, Straßburger M, Heinekamp T, Hong TB, Bzymek KP, Williams JC, Brakhage AA, Kalkum M (2016) The crystal structure of peroxiredoxin Asp f3 provides mechanistic insight into oxidative stress resistance and virulence of Aspergillus fumigatus. Sci Rep 6, 33396.
Joehnk B, Bayram O, Valerius O, Heinekamp T, Jacobsen ID, Mattern D, Brakhage AA, Braus G (2016) SCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatus PLOS Pathog 12(9), e1005899.