(2016)
Application of PARAFAC and OPLS-DA analyses on HPLC fingerprints for the characterization of Hibiscus sabdariffa calyxes.
Quim. Nova 39(2),
160-166.
Dr. Freddy Alexander Bernal
Transfergruppe Antiinfektiva +49 3641 532-1044 freddy.bernal@leibniz-hki.deCurriculum vitae
Forschungsschwerpunkte
- Computer-gestützte Drug Discovery
- Organische Synthese Medikamenten-ähnlicher antimikrobieller Wirkstoffe
Wissenschaftlicher Werdegang
| Since 09.2020 | Chemist for Drug Discovery, Transfer Group Anti-infectives, Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI), Jena, Germany. Topic: Computer-aided discovery and optimization of novel antimicrobials. |
| 08.2015-10.2019 | Doctorate (Doctor of Natural Sciences – Pharmacy), Westfälische Wilhelms – Universität Münster, Münster, Germany. Dissertation title: Qualitative and quantitative structure-activity relationships on 2-phenyl-2,3-dihydrobenzofurans as Leishmanicidal agents. Research advisor: Prof. Dr. Thomas J. Schmidt |
| 02.2012-05.2015 | Research Assistant. Bioorganic Chemistry, Military University Nueva Granada, Cajicá, Colombia. |
| 07.2011-05.2015 | Lecturer, General Chemistry. Department of Chemistry, Military University Nueva Granada, Bogotá, Colombia. |
| 08.2011-12.2013 | Lecturer, Instrumental Analysis and Spectroscopy. Department of Educational Chemistry, Distrital University Francisco Jose de Caldas, Bogotá, Colombia. |
| 02.2010-12.2010 | Lecturer, Organic Chemistry and Analytical Chemistry. Technological Corporation of Bogota, Bogotá, Colombia. |
| 08.2007-10.2009 | Master in Sciences – Chemistry, National University of Colombia, Bogotá, Colombia. Thesis title: Isolation of secondary metabolites from the leaves of Iryanthera ulei Warb. (Myristicaceae), evaluation of their antimicrobial activity and synthesis of one 8-O-4′-neolignan. Research advisor: Prof. Dr. Luis E. Cuca. |
| 02.2002-02.2007 | Bachelor in Chemistry, National University of Colombia, Bogotá, Colombia. |
Publikationen
(2016)
Diazo coupling reaction of catechins and alkylresorcinols with diazotized sulfanilic acid for quantitative purposes in edible sources: method development and validation.
Food Analytical Methods 9(2),
411-418.
(2015)
Molecular docking and multivariate analysis of xanthones as antimicrobial and antiviral agents.
Molecules 20(7),
13165-13204.
(2015)
Chemical profile and antioxidant capacity of calyxes from commercial crops-derived Colombian Roselle (Hibiscus sabdariffa L.).
Medicinal Plants - International Journal of Phytomedicines and Related Industries 7(2),
137-144.
(2015)
A Facile approach toward 8-O-4'-neolignans: synthesis of threo-7',8'-dihydromachilin D through Jacobsen epoxidation
Revista Facultad de Ciencias Básicas 11(1),
114-129.
(2015)
Exploitation of the complexation reaction of ortho-dihydroxylated anthocyanins with aluminum(III) for their quantitative spectrophotometric determination in edible sources.
Food Chem 185,
84-89.
(2014)
In-silico analyses of sesquiterpene-related compounds on selected Leishmania enzyme-based targets.
Molecules 19(5),
5550-5569.
(2014)
Diterpenos de núcleo kaurano como inhibidores de la PTR1 de Leishmania: un estudio in silico.
Revista Facultad de Ciencias Básicas 9(1),
142-152.
(2013)
LC-DAD-UV and LC-ESI-MS-based analyses, antioxidant capacity, and antimicrobial activity of a polar fraction from Iryanthera ulei leaves.
Records of Natural Products 7(2),
152-156.
(2012)
Fingerprint analysis of unfractionated piper plant extracts by HPLC-UV-DAD coupled with chemometric methods.
Journal of the Chilean Chemical Society 57(3),
1256-1261.
