(2025)
In vitro psilocybin synthesis by co-immobilized enzymes.
Chem Eur J
[Epub ahead of print]
Curriculum vitae
Forschungsschwerpunkte
- Biochemische und genetische Grundlagen des Sekundärstoffwechsels basaler Pilze (insbesondere Mucoromyceten und Zoopagomyceten)
- Pharmazeutische und ökologische Bedeutung der Naturstoffe aus basalen Pilzen
- alternative Naturstoffbiosynthese-Strategien
Wissenschaftlicher Werdegang
| seit 2024 | Privatdozent am Institut für Pharmazie, Friedrich-Schiller-Universität, Jena |
| 2017-2024 | Habilitation (Pharmazeutische Mikrobiologie) an der Friedrich-Schiller-Universität Jena |
| 2015-2017 | Post-Doc, Institute Pasteur, Paris, Frankreich |
| 2009-2015 | Promotion (Biochemie) an der Friedrich-Schiller-Universität Jena und dem Hans-Knöll-Institut, Jena |
| 2003-2009 | Diplom (Biochemie/Molekularbiologie) an der Friedrich-Schiller-Universität Jena |
Publikationen
(2025)
Clade III synthases add cyclic and linear terpenoids to the Psilocybe metabolome.
ChemBioChem
[Accepted]
(2024)
Beneficial soil fungus kills predatory nematodes with dehydropeptides translocating into the animal gut.
J Am Chem Soc 146(50),
34702-34710.
(2024)
Interplay between host humoral pattern recognition molecules controls undue immuneresponses against Aspergillus fumigatus.
Nat Commun 15(1),
6966.
(2024)
Parallel evolution of Asco- and Basidiomycete O-Prenyltransferases.
J Nat Prod 87(3),
576-582.
(2023)
A genetic tool to express long fungal biosynthetic genes.
Fungal Biol Biotechnol 10(1),
4.
(2023)
Basidiomycete non-reducing polyketide synthases function independently of SAT domains.
Fungal Biol Biotechnol 10(1),
17.
(2023)
Non-canonical two-step biosynthesis of anti-oomycete indole alkaloids in Kickxellales.
Fungal Biol Biotechnol 1010(1),
19.
(2023)
Insecticidal cyclodepsitetrapeptides from Mortierella alpina.
J Nat Prod 86(7),
1715-1722.
(2023)
A "Magic Mushroom" multi-product sesquiterpene synthase.
ChemBioChem 24(21),
e202300511.
