(2018)
The secreted Candida albicans protein Pra1 disrupts host defense by broadly targeting and blocking complement C3 and C3 activation fragments.
Mol Immunol 93,
266-277.
Prof. Dr. Christine Skerka
AlumniPublikationen
(2018)
Streptococcus pneumoniae from patients with hemolytic uremic syndrome binds human plasminogen via the surface protein PspC and uses plasmin to damage human endothelial cells.
J Infect Dis 217(3),
358-370.
(2018)
The MFHR1 fusion protein is a novel synthetic multitarget complement inhibitor with therapeutic potential.
J Am Soc Nephrol 29(4),
1141-1153.
(2018)
Evaluation of serum sphingolipids and the influence of genetic risk factors in age-related macular degeneration.
PLOS One 13(8),
e0200739.
(2018)
FHR-1 binding impairs factor H-mediated complement evasion by the malaria parasite Plasmodium falciparum.
J Immunol 201(12),
3497-3502.
(2018)
FHR5 binds to laminins, uses separate C3b and surface-binding sites, and activates complement on malondialdehyde-acetaldehyde surfaces.
J Immunol 200(7),
2280-2290.
(2018)
Reply to kang and brooks: Comment on the interpretation of binding of Pra1, the fungal immune evasion protein from Candida albicans to the human C3 and on the conformational changes of C3 upon activation: Kang and brooks optimization of biolayer-interfero.
Mol Immunol 101,
638-639.
(2017)
Anaphylatoxins activate Ca2+, akt/PI3-kinase, and FOXO1/foxP3 in the retinal pigment Epithelium.
Front Immunol 8,
703.
(2017)
Factor H binds to extracellular DNA traps released from human blood monocytes in response to Candida albicans.
Front Immunol 7,
671.
(2017)
Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina.
EMBO Mol Med 9(2),
154-166.