(2019)
Metabolic pathway rerouting in Paraburkholderia rhizoxinica evolved long-overlooked derivatives of coenzyme F420.
ACS Chem Biol 14(9),
2088-2094.
Dr. Gerald Lackner
Synthetische Mikrobiologie · Leiter +49 3641 532-1104 gerald.lackner@leibniz-hki.deCurriculum vitae
Wissenschaftlicher Werdegang
2016 -today | Junior Group Leader |
2014 - 2016 | PostDoc (Feodor Lynen Research Fellowship) ETH Zurich (Jörn Piel) Research focus: Genomics of uncultured natural product producers, biosynthesis of ribosomally produced small molecules |
2011 - 2014 | PostDoc FSU Jena (Dirk Hoffmeister) Research focus: Polyketide and nonribosomal peptide biosynthesis in mushrooms. |
2006 - 2011 | PhD student HKI Jena (Christian Hertweck) Research focus: Genomics of natural product-producing bacterial endosymbionts of fungi. |
2001 - 2006 | Studies of Biochemistry FSU, Jena |
Publikationen
(2019)
Structure elucidation of the syringafactin lipopeptides provides insight in the evolution of nonribosomal peptide synthetases.
Chem Sci 10(48),
10979-10990.
(2019)
Bacteria-induced production of the antibacterial sesquiterpene lagopodin B in Coprinopsis cinerea.
Mol Microbiol 112(2),
605-619.
(2018)
Multi-genome analysis identifies functional and phylogenetic diversity of basidiomycete adenylate-forming reductases.
Fungal Genet Biol 112,
55-63.
(2018)
Precursor-directed diversification of cyclic tetrapeptidic pseudoxylallemycins.
ChemBioChem 19(21),
2307-2311.
(2018)
Bacterial alkaloid biosynthesis: Structural diversity via a minimalistic nonribosomal peptide synthetase.
Cell Chem Biol 25(6),
659-665.
(2017)
One ring to fight them all: The sulfazecin story.
Cell Chem Biol 24(1),
1-2.
(Review)
(2017)
A highly conserved basidiomycete peptide synthetase produces a trimeric hydroxamate siderophore.
Appl Environ Microbiol 83(21),
e01478.
(2017)
Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges.
Proc Natl Acad Sci U S A 114(3),
E347-E356.
(2016)
A Lanthipeptide-like N-Terminal Leader Region Guides Peptide Epimerization by Radical SAM Epimerases: Implications for RiPP Evolution
Angew Chem Int Ed Engl 55(40),
12330-12333.