(2011)
Signal transduction by vascular endothelial growth factor receptors.
Biochem J 437(2),
169-183.

Dr. Sina Gerbach
Forschungskoordination Transfergruppe Antiinfektiva · Projektmanagement +49 3641 532-1335 sina.gerbach@leibniz-hki.deCurriculum vitae
Wissenschaftlicher Werdegang
seit 2016 | Wissenschaftliche Koordination, Leibniz Institut für Naturstoffforschung und Infektionsbiologie - Hans Knöll Institut, Jena |
2011 - 2016 | Postdoc, Prof. P. Bastiaens, Max-Planck-Institut für Molekulare Physiologie, Dortmund, Activity of cMet during liver regeneration |
2009 - 2011 | Postdoc, Prof. L. Claesson-Welsh, Uppsala Universität, Schweden, NRP1 guides VEGFR2-mediated endothelial cell growth and tumor initiation. |
2008 | Postdoc, Prof. C. Thiede, Universitätsklinikum Dresden |
2003 - 2007 | Promotion, Prof. C. Thiede, Universitätsklinikum Dresden, Thema: Rezeptortyrosinkinase FLT3 in leukämischen Zellen |
2002 | Gastwissenschaftler, Prof. H. Sjöström, Universität Kopenhagen, Dänemark |
2003 | Diplom in Biochemie der Ernährung, Universität Potsdam, Thema: G-Protein-gekoppelte Rezeptor F2alpha |
1997 - 2003 | Studium der Ernährungswissenschaft, Universität Potsdam |
Themenfelder
Publikationen
(2011)
Vascular endothelial growth factors and receptors: anti-angiogenic therapy in the treatment of cancer.
Mol Aspects Med 32(2),
88-8111.
(2010)
Impact of CXCR4 inhibition on FLT3-ITD-positive human AML blasts.
Exp Hematol 38(3),
180-190.
(2010)
VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts.
EMBO J 29(8),
1377-1388.
(2010)
Mechanisms of resistance against PKC412 in resistant FLT3-ITD positive human acute myeloid leukemia cells.
Ann Hematol 89(7),
653-662.
(2009)
Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality.
Blood 113(15),
3568-3576.
(2009)
Efficient production of bioactive recombinant human Flt3 ligand in E. coli.
Protein J 28(2),
57-65.
(2008)
Abnormal localization and accumulation of FLT3-ITD, a mutant receptor tyrosine kinase involved in leukemogenesis.
Cells Tissues Organs 188(1-2),
225-235.
(2006)
Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML).
Blood 107(10),
4011-4020.
(2003)
Identification by site-directed mutagenesis of amino acids contributing to ligand-binding specificity or signal transduction properties of the human FP prostanoid receptor.
Biochem J 371(Pt 2),
443-449.