Gianni Panagiotou

Prof. Dr. Gianni Panagiotou

Microbiome Dynamics · Leitung +49 3641 532-1759 gianni.panagiotou@leibniz-hki.de

Curriculum vitae

Forschungsschwerpunkte
  • Medizinische & Umweltmetagenomik: Mensch, Maus, Pflanzen, marine Lebewesen
  • Systembiologie: Integration von –omics-Daten; Molekül/ Protein & Protein/ Protein Netzwerke
  • Synthetische Biologie: Metabolische Modellierung auf Genomausmaß, Design von Probiotika, Entdeckung von Postbiotika

Publikationen

Häder A#, Schäuble S#, Gehlen J, Thielemann N, Buerfent BC, Schüller V, Hess T, Wolf T, Schröder J, Weber M, Hünniger K, Löffler J, Vylkova S, Panagiotou G, Schumacher J, Kurzai O (2023) Pathogen-specific innate immune response patterns are distinctly affected by genetic diversity. Nat Commun 14(1), 3239.
Kelani AA, Bruch A, Rivieccio F, Visser C, Krüger T, Weaver D, Pan X, Schaeuble S, Panagiotou G, Kniemeyer O, Bromley MJ, Bowyer P, Barber AE, Brakhage AA, Blango MG (2023) Disruption of the A. fumigatus RNA interference machinery alters the conidial transcriptome. RNA 29(7), 1033-1050.
Leung H, Xiong L, Ni Y, Busch A, Bauer M, Press AT, Panagiotou G (2023) Impaired flux of bile acids from the liver to the gut reveals microbiome-immune interactions associated with liver damage. NPJ Biofilms and microbiomes 9(1), 35.
Mirhakkak MH*, Chen X*, Heinekamp T, Sae-Ong T, Xu LL, Ni Y, Kurzai O, Barber AE, Brakhage AA, Boutin S, Schäuble S#, Panagiotou G# (2023) Genome-scale Metabolic modeling of Aspergillus fumigatus strains reveals growth dependencies on the lung microbiome. Nat Commun 14(1), 4369.
Ni Y*, Qian L*, Leal Siliceo S*, Long X*, Nychas E, Liu Y, Ismaiah MJ, Leung H, Zhang L, Gao Q, Wu Q, Zhang Y, Jia Xi, Liu S, Yuan R, Zhou L, Wang X, Li Q, Zhao Y, El-Nezami H, Xu A, Xu G#, Li H#, Panagiotou G#, Jia W# (2023) Resistant starch decreases intrahepatic triglycerides in NAFLD patients via gut microbiome alterations. Cell Metab 35(9), 1530-1547.
Patumcharoenpol P, Kingkaw A, Nakphaichit M, Chatchatee P, Suratannon N#, Panagiotou G, Vongsangnak W# (2023) Exploring longitudinal gut microbiome towards metabolic functional changes associated in atopic dermatitis in early childhood. Biology (Basel) 12(9), 1262-1277.
Refisch A#, Sen ZD, Klassert TE, Busch A, Besteher B, Danyeli LV, Helbing D, Schulze-Späte U, Stallmach A, Bauer M, Panagiotou G, Jacobsen ID, Slevogt H, Opel N, Walter M (2023) Microbiome and immuno-metabolic dysregulation in patients with major depressive disorder with atypical clinical presentation. Neuropharmacology 235, 109568. (Review)
Schruefer S, Pschibul A, Wong SSW, Sae-Ong T, Wolf T, Schäuble S, Panagiotou G, Brakhage AA, Aimanianda V, Kniemeyer O, Ebel F (2023) Distinct transcriptional responses to fludioxonil in Aspergillus fumigatus and its ΔtcsC and Δskn7 mutants reveal a crucial role for Skn7 in the cell wall reorganizations triggered by this antifungal. BMC Genomics 24(1), 684.
Seelbinder B#, Lohinai Z*, Vazquez-Uribe R, Brunke S, Chen X, Mirhakkak M, Lopez-Escalera S, Dome B, Megyesfalvi Z, Berta J, Galffy G, Dulka E, Wellejus A, Weiss GJ, Bauer M, Hube B, Sommer MOA, Panagiotou G (2023) Candida expansion in the gut of lung cancer patients associates with an ecological signature that supports growth under dysbiotic conditions. Nat Commun 14(1), 2673.
Soll D, Arunkumar M, Alkhalaf M, Sun S, Nguyen T, Chu C, Lutz V, Schäuble S, Garcia-Ribelles I, Mueller M, Michalke B, Panagiotou G, Schatzlmaier P, Stockinger H, Schamel W, Huber M, Zielinski C (2023) Sodium chloride in the tumor microenvironment enhances T-cell metabolic fitness and cytotoxicity. BioRxiv [Preprint]

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