Human natural killer cells acting as phagocytes against Candida albicans and mounting an inflammatory response that modulates neutrophil antifungal activity.

Voigt J, Hünniger K, Bouzani M, Jacobsen ID, Barz D, Hube B, Löffler J, Kurzai O (2014) Human natural killer cells acting as phagocytes against Candida albicans and mounting an inflammatory response that modulates neutrophil antifungal activity. J Infect Dis 209(4), 616-626. PubMed

Abstract

Natural killer (NK) cells are innate lymphocytes with potent cytotoxic activity. Whereas activity of NK cells has been demonstrated against the fungal pathogens Aspergillus fumigatus and Cryptococcus neoformans, little was known about their interaction with Candida albicans.

Beteiligte Abteilungen und Gruppen

Mikrobielle Pathogenitätsmechanismen Fungal Septomics Mikrobielle Immunologie

HKI-Autoren

Prof. Dr. Bernhard Hube Prof. Dr. Oliver Kurzai Prof. Dr. Ilse Denise Jacobsen Dr. Kerstin Hünniger

Themenfelder

Interaktion mit Immunzellen (MPM)

Identifier

doi: 10.1093/infdis/jit574 PMID: 24163416