(2017)
Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges.
Proc Natl Acad Sci U S A 114(3),
E347-E356.
Dr. Gerald Lackner
Synthetische Mikrobiologie · Leiter +49 3641 532-1104 gerald.lackner@leibniz-hki.deCurriculum vitae
Wissenschaftlicher Werdegang
| 2016 -today | Junior Group Leader |
| 2014 - 2016 | PostDoc (Feodor Lynen Research Fellowship) ETH Zurich (Jörn Piel) Research focus: Genomics of uncultured natural product producers, biosynthesis of ribosomally produced small molecules |
| 2011 - 2014 | PostDoc FSU Jena (Dirk Hoffmeister) Research focus: Polyketide and nonribosomal peptide biosynthesis in mushrooms. |
| 2006 - 2011 | PhD student HKI Jena (Christian Hertweck) Research focus: Genomics of natural product-producing bacterial endosymbionts of fungi. |
| 2001 - 2006 | Studies of Biochemistry FSU, Jena |
Publikationen
(2016)
A lanthipeptide-like N-terminal leader region guides peptide epimerization by radical SAM epimerases: implications for RiPP evolution.
Angew Chem Int Ed 55(40),
12330-12333.
(2016)
Ectomycorrhizal fungi decompose soil organic matter using oxidative mechanisms adapted from saprotrophic ancestors.
New Phytol 209,
1705-1719.
(2016)
A fivefold parallelized biosynthetic process secures chlorination of Armillaria mellea (honey mushroom) toxins.
Appl Environ Microbiol 82,
1196-1204.
(2015)
Genome sequence of mushroom soft-rot pathogen Janthinobacterium agaricidamnosum.
Genome Announc 3(2),
pii: e00277-15.
(2015)
Genetic engineering activates biosynthesis of aromatic fumaric acid amides in the human pathogen Aspergillus fumigatus.
Appl Environ Microbiol 81,
1594-1600.
(2015)
Activity of α-aminoadipate reductase depends on the N-terminally extending domain.
ChemBioChem 16,
1426-1430.
(2015)
Insights on the evolution of mycoparasitism from the genome of Clonostachys rosea.
Genome Biol Evol 7,
465-480.
(2015)
Structure, genetics and function of an exopolysaccharide produced by a bacterium living within fungal hyphae.
ChemBioChem 16(3),
387-392.
(2014)
Biosynthesis of the halogenated mycotoxin aspirochlorine in koji mold involves a cryptic amino acid conversion.
Angew Chem Int Ed 53,
13409-13413.