Fourier transform (FT)-artifacts and power-function resolution filter in Fourier transform mass spectrometry.

Kanawati B, Bader TM, Wanczek KP, Li Y, Schmitt-Kopplin P (2017) Fourier transform (FT)-artifacts and power-function resolution filter in Fourier transform mass spectrometry. Rapid Commun Mass Spectrom 31(19), 1607-1615.

Abstract

Peak picking algorithms in mass spectrometry face the challenge of picking the correct signals from a mass spectrum. In some cases signal wiggles (side lobes) are also chosen in the produced mass list as if they were real signals. Constraints which are defined in such algorithms do not always guarantee wiggle-free accurate mass list generation out of raw mass spectra. This problem intensifies with acquisitions, which are accompanied by longer transients. Thus, the problem represents a contemporary issue, which propagates with modern high-memory digitizers and exists in both MS and MS/MS spectra.

Leibniz-HKI-Autor*innen

Yan Li

Identifier

doi: 10.1002/rcm.7940

PMID: 28703318