Dr. Freddy Alexander Bernal

Alumni

Publikationen

Keiff F, Bernal FA, Joch M, Jacques Dit Lapierre TJW, Li Y, Liebing P, Dahse HM, Vilotijevic I, Kloss F (2024) Modulation of the Meisenheimer complex metabolism of nitro-benzothiazinones by targeted C-6 substitution. Commun Chem 7(1), 153.
Torres-Gómez H, Keiff F, Hortschansky P, Bernal F, Kerndl V, Meyer F, Messerschmidt N, Dal Molin M, Krüger T, Rybniker J, Brakhage AA, Kloss F (2024) Replacement of the essential nitro group by electrophilic warheads towards nitro-free antimycobacterial benzothiazinones. Eur J Med Chem 279, 116849.
Keiff F, Jacques dit Lapierrev TJW, Bernal F, Kloss F (2023) Design and synthesis of benzofuran- and naphthalene-fused thiazinones as antimycobacterial agents. Arch Pharm (Weinheim) 356(11), e2300356.
Bernal FA, Coy-Barrera E (2022) Composition and antifungal activity of the alkaloidal fraction of Lupinus mirabilis leaves: A biochemometrics-based exploration. Molecules 27(9), 2832.
Bernal FA, Hammann P, Kloss F (2022) Natural products in antibiotic development: is the success story over? Curr Opin Biotechnol 78, 102783. (Review)
Schieferdecker S, Bernal FA, Wojtas KP, Keiff F, Li Y, Dahse HM, Kloss F (2022) Development of predictive classification models for whole cell antimycobacterial activity of benzothiazinones. J Med Chem 65(9), 6748-6763.
Bernal FA, Gerhards M, Kaiser M, Wünsch B, Schmidt TJ (2020) (±)-trans-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: Synthesis, in vitro evaluation and SAR analysis. Eur J Med Chem 205, 112493.
Bernal FA, Kaiser M, Wünsch B, Schmidt TJ (2020) Structure-activity relationships of cinnamate ester analogues as potent antiprotozoal agents. ChemMedChem 15(1), 68-78.
Martin B, Schepmann D, Bernal FA, Schmidt TJ, Che T, Loser K, Wünsch B (2020) Enantiomerically pure quinoline-based κ-opioid receptor agonists: Chemoenzymatic synthesis and pharmacological evaluation. ChemMedChem 15(15), 1408-1420.
Sánchez-Suárez J, Bernal FA, Coy-Barrera E (2020) Colombian contributions fighting leishmaniasis: A systematic review on antileishmanials combined with chemoinformatics analysis. Molecules 25(23), 5704.