Dr. Kyle Dunbar

Alumni

Publikationen

Ishida K, Litomska A, Dunbar KL, Hertweck C (2024) An enzymatic prodrug-like route to thio and selenoamides. Angew Chem Int Ed Engl , e202404243.
Dell M, Dunbar KL, Hertweck C (2022) Ribosome-independent peptide biosynthesis: the challenge of a unifying nomenclature. Nat Prod Rep 39(3), 453-459. (Review)
Gude F, Molloy EM, Horch T, Dell M, Dunbar KL, Krabbe J, Groll M, Hertweck C (2022) A specialized polythioamide-binding protein confers antibiotic self-resistance in anaerobic bacteria. Angew Chem Int Ed 61(37), e202206168.
Horch T, Molloy EM, Bredy F, Haensch VG, Scherlach K, Dunbar KL, Franke J, Hertweck C (2022) Alternative benzoxazole assembly discovered in anaerobic bacteria provides access to privileged heterocyclic scaffold. Angew Chem Int Ed 61(32), e202205409.
Molloy EM, Dell M, Haensch VG, Dunbar KL, Feldmann R, Oberheide A, Seyfarth L, Kumpfmüller J, Horch T, Arndt HD, Hertweck C (2021) Enzyme-primed native chemical ligation produces autoinducing cyclopeptides in clostridia. Angew Chem Int Ed 60(19), 10670-10679.
Dunbar KL, Dell M, Gude F, Hertweck C (2020) Reconstitution of polythioamide antibiotic backbone formation reveals unusual thiotemplated assembly strategy. Proc Nat Acad Sci USA 117(16), 8850-8858.
Dunbar KL, Dell M, Molloy EM, Büttner H, Kumpfmüller J, Hertweck C (2020) An unexpected split-merge pathway to the symmetric nonribosomal peptide antibiotic closthioamide. Angew Chem Int Ed 60(8), 4104-4109.
Dunbar KL, Dell M, Molloy EM, Kloss F, Hertweck C (2019) Reconstitution of iterative thioamidation in closthioamide biosynthesis reveals a novel nonribosomal peptide backbone-tailoring strategy. Angew Chem Int Ed 58(37), 13014-13018.
Dunbar KL, Büttner H, Molloy EM, Dell M, Kumpfmüller J, Hertweck C (2018) Genome editing reveals novel thiotemplated assembly of polythioamide antibiotics in anaerobic bacteria. Angew Chem Int Ed 57(43), 14080-14084.
Litomska A, Ishida K, Dunbar KL, Boettger M, Coyne S, Hertweck C (2018) Enzymatic thioamide tormation in a bacterial antimetabolite pathway. Angew Chem Int Ed 57(36), 11574-11578.