(2018)
Hürden und Aussichten neuer antimikrobieller Konzepte in Forschung und Entwicklung. [Obstacles and perspectives of new antimicrobial concepts within research and development].
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 61(5),
595-605.
(Review)
Dr. Sina Gerbach
Forschungskoordination Transfergruppe Antiinfektiva · Projektmanagement +49 3641 532-1335 sina.gerbach@leibniz-hki.deCurriculum vitae
Wissenschaftlicher Werdegang
seit 2016 | Wissenschaftliche Koordination, Leibniz Institut für Naturstoffforschung und Infektionsbiologie - Hans Knöll Institut, Jena |
2011 - 2016 | Postdoc, Prof. P. Bastiaens, Max-Planck-Institut für Molekulare Physiologie, Dortmund, Activity of cMet during liver regeneration |
2009 - 2011 | Postdoc, Prof. L. Claesson-Welsh, Uppsala Universität, Schweden, NRP1 guides VEGFR2-mediated endothelial cell growth and tumor initiation. |
2008 | Postdoc, Prof. C. Thiede, Universitätsklinikum Dresden |
2003 - 2007 | Promotion, Prof. C. Thiede, Universitätsklinikum Dresden, Thema: Rezeptortyrosinkinase FLT3 in leukämischen Zellen |
2002 | Gastwissenschaftler, Prof. H. Sjöström, Universität Kopenhagen, Dänemark |
2003 | Diplom in Biochemie der Ernährung, Universität Potsdam, Thema: G-Protein-gekoppelte Rezeptor F2alpha |
1997 - 2003 | Studium der Ernährungswissenschaft, Universität Potsdam |
Themenfelder
Publikationen
(2016)
In Situ Proximity Ligation Assay (In Situ PLA) to Assess PTP-Protein Interactions.
Methods Mol Biol 1447,
217-242.
(2014)
NRP1 presented in trans to the endothelium arrests VEGFR2 endocytosis, preventing angiogenic signaling and tumor initiation.
Dev Cell 28(6),
633-646.
(2013)
VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation.
Nat Commun 4,
1672.
(2013)
Features of Ras activation by a mislocalized oncogenic tyrosine kinase: FLT3 ITD signals through K-Ras at the plasma membrane of acute myeloid leukemia cells.
J Cell Sci 126(Pt 20),
4746-4755.
(2013)
Autotaxin is expressed in FLT3-ITD positive acute myeloid leukemia and hematopoietic stem cells and promotes cell migration and proliferation.
Exp Hematol 41(5),
444-461.e4.
(2012)
Neuropilin signalling in angiogenesis.
Biochem Soc Trans 40(1),
20-25.
(2012)
Signal transduction by vascular endothelial growth factor receptors.
Cold Spring Harb Perspect Med 2(7),
a006502.
(2011)
Signal transduction by vascular endothelial growth factor receptors.
Biochem J 437(2),
169-183.
(2011)
Vascular endothelial growth factors and receptors: anti-angiogenic therapy in the treatment of cancer.
Mol Aspects Med 32(2),
88-8111.