Florian Kloß

Dr. Florian Kloß

Transfergruppe Antiinfektiva · Leitung

Telefon: +49 3641 532-1356 Telefax: +49 3641 532-2356 E-Mail: florian.kloss@leibniz-hki.de

Publikationen

Dunbar KL, Dell M, Molloy EM, Kloss F, Hertweck C (2019) Reconstitution of Iterative Thioamidation in Closthioamide Biosynthesis Reveals a Novel Nonribosomal Peptide Backbone-Tailoring Strategy. Angew Chem Int Ed Engl , Details PubMed

Fischer D, Gessner G, Fill TP, Barnett R, Tron K, Dornblut K, Kloss F, Stallforth P, Hube B, Heinemann SH, Hertweck C, Scherlach K, Brunke S (2019) Disruption of membrane integrity by the bacteria-derived antifungal jagaricin. Antimicrob Agents Chemother , Details PubMed

Kloss F, Neuwirth T, Haensch VG, Hertweck C (2018) Metal-Free Synthesis of Pharmaceutically Important Biaryls by Photosplicing. Angew Chem Int Ed 57(44), 14476-14481. Details PubMed

Kloss F, Krchnak V, Krchnakova A, Schieferdecker S, Dreisbach J, Krone V, Möllmann U, Hoelscher M, Miller MJ (2017) In Vivo Dearomatization of the Potent Antituberculosis Agent BTZ043 via Meisenheimer Complex Formation. Angew Chem Int Ed 56(8), 2187-2191. Details PubMed

Chiriac AI, Kloss F, Krämer J, Vuong C, Hertweck C, Sahl HG (2015) Mode of action of closthioamide: the first member of the polythioamide class of bacterial DNA gyrase inhibitors. J Antimicrob Chemother 70(9), 2576-2588. Details PubMed

Kloss F, Chiriac AI, Hertweck C (2014) Mapping of the modular closthioamide architecture reveals crucial motifs of polythioamide antibiotics. Chemistry 20(47), 15451-15458. Details PubMed

Pidot SJ, Coyne S, Kloß F, Hertweck C (2014) Antibiotics from neglected bacterial sources. Int J Med Microbiol 304(1), 14-22. Details PubMed

Ross C, Scherlach K, Kloss F, Hertweck C (2014) The molecular basis of conjugated polyyne biosynthesis in phytopathogenic bacteria. Angew Chem Int Ed Engl 53(30), 7794-7798. Details PubMed

Behnken S, Lincke T, Kloss F, Ishida K, Hertweck C (2012) Antiterminator-mediated unveiling of cryptic polythioamides in an anaerobic bacterium. Angew Chem Int Ed Engl 51(10), 2425-2428. Details PubMed