
Dr. Sebastian Schieferdecker
Transfergruppe Antiinfektiva
(2020) Oak-associated negativicute equipped with ancestral aromatic polyketide synthase produces antimycobacterial dendrubins. Chem Eur J 26(58), 13147-13151. Details PubMed Open Access PDF
(2019) Clostrindolin is an antimycobacterial pyrone alkaloid from Clostridium beijerinckii. Org Biomol Chem 17(25), 6119-6121. Details PubMed
(2019) Biosynthesis of diverse antimicrobial and antiproliferative acyloins in anaerobic bacteria. ACS Chem Biol 14(7), 1490-1497. Details PubMed
(2017) Structure of ralsolamycin, the inter-kingdom morphogen of the crop plant pathogen Ralstonia solanacearum GMI1000. Org Lett 19, 4868-4871. Details
(2017) In Vivo Dearomatization of the Potent Antituberculosis Agent BTZ043 via Meisenheimer Complex Formation. Angew Chem Int Ed 56(8), 2187-2191. Details PubMed
(2016) An Iterative O-Methyltransferase Catalyzes 1,11-Dimethylation of Aspergillus fumigatus Fumaric Acid Amides. ChemBioChem 17, 1813-1817. Details PubMed
(2016) Variochelins, lipopeptide siderophores from Variovorax boronicumulans discovered by genome mining. J Nat Prod 79(4), 865-872. Details PubMed
(2016) The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo. Biochem Pharmacol 112, 60-71. Details PubMed
(2016) A fast and efficient method for the preparation of the 5-lipoxygenase inhibitor myxochelin A. Tetrahedron Lett 57, 1359-1360. Details
(2015) Harnessing enzymatic promiscuity in myxochelin biosynthesis for the production of 5-lipoxygenase inhibitors. ChemBioChem 16, 2445-2450. Details
(2015) Structure and absolute configuration of auriculamide, a natural product from the predatory bacterium Herpetosiphon aurantiacus. Eur J Org Chem 14, 3057-3062. Details
(2015) Myxochelins target human 5-lipoxygenase. J Nat Prod 78(2), 335-338. Details PubMed
(2014) New myxothiazols from the predatory bacterium Myxococcus fulvus. J Antibiot 67(7), 519-525. Details PubMed
(2014) Structure and Biosynthetic Assembly of Gulmirecins, Macrolide Antibiotics from the Predatory Bacterium Pyxidicoccus fallax. Chem Eur J 20, 15933-15940. Details PubMed