Transfergruppe Antiinfektiva

Bitar L, Uphaus T, Thalman C, Muthuraman M, Gyr L, Ji H, Domingues M, Endle H, Groppa S, Steffen F, Koirala N, Fan W, Ibanez L, Heitsch L, Cruchaga C, Lee JM, Kloss F, Bittner S, Nitsch R, Zipp F, Vogt J (2022) Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke. Sci Transl Med 14(641), eabk0135.

Haensch V, Neuwirth T, Bergner A, ,Bruhnke J, Kloss F, Hertweck C (2022) Sustainable and highly controlled aryl couplings revealed by systematic assessment of photoactivatable linkers. Chemical Science 13(19), 5680-5686.

Schieferdecker S, Bernal FA, Wojtas KP, Keiff F, Li Y, Dahse HM, Kloss F (2022) Development of predictive classification models for whole cell antimycobacterial activity of benzothiazinones. J Med Chem 65(9), 6748-6763.

Böttcher S, Hartung S, Meyer F, Rummler S, Voigt K, Walther G, Hochhaus A, von Lilienfeld-Toal M, Jahreis S (2021) Human mucosal-associated invariant T cells respond to Mucorales species in a MR1-dependent manner. Med Mycol 59(5), 505-509.

Brantl V, Boysen JM, Yap A, Golubtsov E, Ruf D, Heinekamp T, Straßburger M, Dichtl K, Haas H, Hillmann F, Wagener J (2021) Peroxiredoxin Asp f3 is essential for Aspergillus fumigatus to overcome iron limitation during infection. mBio 12(4), e0097621.

Schlosser N, Espino-Martínez J, Kloss F, Meyer F, Bardl B, Rosenbaum MA, Regestein L (2021) Host nutrition-based approach for biotechnological production of the antifungal cyclic lipopeptide jagaricin. J Biotechnol 336, 1-9.

Stein J, Schlosser N, Bardl B, Peschel G, Meyer F, Kloss F, Rosenbaum MA, Regestein L (2021) Scalable downstream method for the cyclic lipopetidejagaricin. Eng Life Sci , 1-7.

Blei F, Dörner S, Fricke J, Baldeweg F, Trottmann F, Komor AJ, Meyer F, Hertweck C, Hoffmeister D (2020) Simultaneous production of psilocybin and a cocktail of β-carboline monoamine oxidase inhibitors in ‘magic’ mushrooms. Chem Eur J 26(3), 729-734.

Frawley D, Stroe MC, Oakley BR, Heinekamp T, Straßburger M, Fleming AB, Brakhage AA, Bayram Ö (2020) The pheromone module SteC-MkkB-MpkB-SteD-HamE regulates development, stress responses and secondary metabolism in Aspergillus fumigatus. Front Microbiol 11, 811.

Ishida K, Shabuer G, Schieferdecker S, Pidot SJ, Stinear TP, Knuepfer U, Cyrulies M, Hertweck C (2020) Oak-associated negativicute equipped with ancestral aromatic polyketide synthase produces antimycobacterial dendrubins. Chem Eur J 26(58), 13147-13151.