Transfergruppe Antiinfektiva

Fischer D, Gessner G, Fill TP, Barnett R, Tron K, Dornblut K, Kloss F, Stallforth P, Hube B, Heinemann SH, Hertweck C, Scherlach K, Brunke S (2019) Disruption of membrane integrity by the bacteria-derived antifungal jagaricin. Antimicrob Agents Chemother 63(9), e00707-19.

Haensch VG, Neuwirth T, Steinmetzer J, Kloss F, Beckert R, Gräfe S, Kupfer S, Hertweck C (2019) Metal-free aryl cross-coupling directed by traceless linkers. Chem Eur J 25(70), 16068-16073.

König S, Pace S, Pein H, Heinekamp T, Kramer J, Romp E, Straßburger M, Troisi F, Proschak A, Dworschak J, Scherlach K, Rossi A, Sautebin L, Haeggström JZ, Hertweck C, Brakhage AA, Gerstmeier J, Proschak E, Werz O (2019) Gliotoxin from Aspergillus fumigatus abrogates leukotriene B4 formation through inhibition of leukotriene A4 hydrolase. Cell Chem Biol 26(4), 524-534.

Manfiolli AO, Siqueira FS, Dos Reis TF, Van Dijck P, Schrevens S, Hoefgen S, Föge M, Straßburger M, de Assis LJ, Heinekamp T, Rocha MC, Janevska S, Brakhage AA, Malavazi I, Goldman GH, Valiante V (2019) Mitogen-activated protein kinase cross-talk interaction modulates the production of melanins in Aspergillus fumigatus. mBio 10(2), e00215-19.

Schieferdecker S, Shabuer G, Knuepfer U, Hertweck C (2019) Clostrindolin is an antimycobacterial pyrone alkaloid from Clostridium beijerinckii. Org Biomol Chem 17(25), 6119-6121.

Schieferdecker S, Shabuer G, Letztel AC, Urbansky B, Ishida-Ito M, Ishida K, Cyrulies M, Dahse HM, Pidot S, Hertweck C (2019) Biosynthesis of diverse antimicrobial and antiproliferative acyloins in anaerobic bacteria. ACS Chem Biol 14(7), 1490-1497.

Kloss F, Gerbach S (2018) Hürden und Aussichten neuer antimikrobieller Konzepte in Forschung und Entwicklung. [Obstacles and perspectives of new antimicrobial concepts within research and development]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 61(5), 595-605. (Review)

Kloss F, Neuwirth T, Haensch VG, Hertweck C (2018) Metal-free synthesis of pharmaceutically important biaryls by photosplicing. Angew Chem Int Ed 57(44), 14476-14481.

Long N, Orasch T, Zhang S, Gao L, Xu X, Hortschansky P, Ye J, Zhang F, Xu K, Gsaller F, Straßburger M, Binder U, Heinekamp T, Brakhage AA, Haas H, Lu L (2018) The Zn2Cys6-type transcription factor LeuB cross-links regulation of leucine biosynthesis and iron acquisition in Aspergillus fumigatus. PLOS Genet 14(10), e1007762.

Voltersen V, Blango MG, Herrmann S, Schmidt F, Heinekamp T, Strassburger M, Krüger T, Bacher P, Lother J, Weiss E, Hünniger K, Liu H, Hortschansky P, Scheffold A, Loeffler J, Krappmann S, Nietzsche S, Kurzai O, Einsele H, Kniemeyer O, Filler S, Reichard U, Brakhage AA (2018) Proteome analysis reveals the conidial surface protein CcpA essential for virulence of the pathogenic fungus Aspergillus fumigatus. mBio 9(5), e01557-18.