BEGIN:VCALENDAR PRODID:-//eluceo/ical//2.0/EN VERSION:2.0 CALSCALE:GREGORIAN BEGIN:VEVENT UID:c787bb3ca10f6150cdacd683d8384bcb DTSTAMP:20240413T102123Z SUMMARY:Biotechnology from Home Office - Miniaturization\, Automation\, and Digitalization in Bioprocess Development DESCRIPTION:In recent years\, the speed of microbial strain generation base d on synthetic biology tools is steadily increasing. Today\, one lab can e asily produce 10.000 different mutants of an industrially used platform or ganism in one week. In contrast\, the throughput of bioprocess devel-opmen t stays way behind. Widening this bottleneck is a central research topic i n the Jülich biotechnology institute IBG-1. Miniaturization of typical bi oprocess development operations by using parallel micro cultivation device s integrated with lab robots has significantly changed the way in which bi oprocesses are developed today. However\, before such automation platforms can replace classical lab scale bioreactors\, high efforts have to be tak en to achieve reproducible and quantitatively reliable cultivations in the micro-titer scale. Once this works\, scientists are confronted with a flo od of quantitative information\, which cannot be handled anymore within cl assical workflows. This is where digitalization and data science comes in. Modern workflow systems and artificial intelligence algorithms can perfor m many (but not all) tasks automatically\, thus assisting human deci-sion- making. The talk will illustrate the established experimental and digital workflows with examples from process performance indicator estimation\, mi cro cultivation of filamentous fungi\, and strain selection. At the end\, it will become clear\, that – at least in bioprocess de-velopment – “Biotechnology from Home Office” is already reality. URL: DTSTART:20200929T110000 DTEND:20200929T110000 LOCATION:online END:VEVENT BEGIN:VTIMEZONE TZID:Europe/Berlin BEGIN:DAYLIGHT DTSTART:20200929T110000 TZNAME:CEST TZOFFSETTO:+0200 TZOFFSETFROM:+0200 END:DAYLIGHT END:VTIMEZONE END:VCALENDAR