Curriculum vitae

Main Research Areas
  • Infection biology of human pathogenic fungi (Candida albicans)
  • Immunology of fungal infections
  • Host-pathogen interactions
  • Fungal adaptation to the host
Professional Career
Since
05/2020
Junior Research Group Leader, Leibniz Institute of Natural Product Research and Infection Biology - Hans Knoell Institute, Adaptive Pathogenicity Strategies
05/2018-
05/2020
Alexander von Humboldt Foundation Postdoctoral Fellowship, Leibniz Institute of Natural Product Research and Infection Biology - Hans Knoell Institute, Dept. Microbial Pathogenicity Mechanisms
03/2018-04/2018 Language Course German, Dresden, Germany
08/2015-03/2018 Postdoctoral researcher, Radboud University Medical Center, Department of Internal medicine, Nijmegen Institute for Infectious Diseases. Project: The development of novel immunomodulatory strategies for disseminated fungal infections
10/2010-05/2015 Phd, Radboud University Nijmegen Medical Center, department of internal medicine, Nijmegen, The Netherlands. Project: Pattern recognition and cytokine signalling pathways in the host defence against Aspergillus fumigatus
02/2008-08/2010 M.Sc. Medical Biology, Radboud University, Nijmegen, The Netherlands
07/2003-07/2007 B.Sc. Biology and Medical Laboratory Research, Saxion University of Applied Sciences, Enschede, The Netherlands
Awards · Appointments · Scientific Activities
2021 Research award of the German speaking society for Mycology (DMykG)
2021 Science Award Life Sciences and Physics 2021 Beutenberg Campus e.V. Jena
Since 2021 Member and PI of the DFG SFB/TR 124 programme "Pathogenic fungi and their human host: Networks of interaction – FungiNet'"
Since 2020 DFG Emmy Noether grant
2020 Journal of Fungi Travel Award
2020 Co-Organizer of the FEBS advanced practical course “State-of-the-art infection models for human pathogenic fungi” in Jena, Germany
2019 PLoS Pathogens Postdoctoral Poster Award, Advanced lecture course on Human Fungal Pathogens
2019 ESCMID Research Grant 2019
2019 Co-organizer of the winter school of the FunHoMic Marie Curie International Training Network
2018-2021 Two publication awards of the Deutschsprachigen Mykologischen Gesellschaft (DMykG; as co-author)
2018 Humboldt Research Fellowship for Postdoctoral Researchers
2018 Golden pipette award by the Laboratory for Experimental Internal Medicine Radboud University Nijmegen Medical center
2016 3rd prize for best thesis by the Radboud institute for molecular life sciences (RIMLS)
2015 Van Beckum thesis Award for best PhD thesis in the field of immunology by the Dutch society for Immunology (NVVI)
2015 Youth development Prize by the German speaking society for Mycology (DMykG)
Since 2014 Ad hoc reviewer for 19 journals eLife, PLoS Pathogens, mBio, Journal of Infectious Diseases, Frontiers Immunology, Cellular Microbiology, FEMS microbiology letters, Microbial Pathogenesis, Virulence, and others
2013 ALLFUN Investigators Award

Publications

Maurer M, Gresnigt MS, Last A, Wollny T, Berlinghof F, Pospich R, Cseresnyes Z, Medyukhina A, Graf K, Gröger M, Raasch M, Siwczak F, Nietzsche S, Jacobsen ID, Figge MT, Hube B, Huber O, Mosig AS (2019) A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies. Biomaterials 220, 119396.
Assendorp EL, Gresnigt MS, Sprenkeler EGG, Meis JF, Dors N, van der Linden JWM, Henriet SSV (2018) Adjunctive interferon-γ immunotherapy in a pediatric case of Aspergillus terreus infection. Eur J Clin Microbiol Infect Dis 37(10), 1915-1922.
Gresnigt MS, Becker KL, Leenders F, Alonso MF, Wang X, Meis JF, Bain JM, Erwig LP, van de Veerdonk FL (2018) Differential Kinetics of Aspergillus nidulans and Aspergillus fumigatus Phagocytosis. J Innate Immun 10(2), 145-160.
Gresnigt MS, Cunha C, Jaeger M, Gonçalves SM, Malireddi RKS, Ammerdorffer A, Lubbers R, Oosting M, Rasid O, Jouvion G, Fitting C, Jong DJ, Lacerda JF, Campos A, Melchers WJG, Lagrou K, Maertens J, Kanneganti TD, Carvalho A, Ibrahim-Granet O, van de Veerdonk FL (2018) Genetic deficiency of NOD2 confers resistance to invasive aspergillosis. Nat Commun 9(1), 2636.
Kasper L, König A, Koenig PA, Gresnigt MS, Westman J, Drummond RA, Lionakis MS, Groß O, Ruland J, Naglik JR, Hube B (2018) The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes. Nat Commun 9(1), 4260.
Workum JD, de Jong SW, Gresnigt MS, Becker KL, Pickkers P, van de Veerdonk FL, Heijdra YF, Kolwijck E (2018) Microbiological and immunological characteristics of a lethal pulmonary Aspergillus niger infection in a non-neutropenic patient. Med Mycol Case Rep 21, 4-7.
Armstrong-James D, Brown GD, Netea MG, Zelante T, Gresnigt MS, van de Veerdonk FL, Levitz SM (2017) Immunotherapeutic approaches to treatment of fungal diseases. Lancet Infect Dis 17(12), e393-e402.
Arts RJ, Gresnigt MS, Joosten LA, Netea MG (2017) Cellular metabolism of myeloid cells in sepsis. J Leukoc Biol 101(1), 151-164.
Dewi IMW, van de Veerdonk FL, Gresnigt MS (2017) The Multifaceted Role of T-Helper Responses in Host Defense against Aspergillus fumigatus. J Fungi (Basel) 3(4),
Domínguez-Andrés J, Arts RJW, Ter Horst R, Gresnigt MS, Smeekens SP, Ratter JM, Lachmandas E, Boutens L, van de Veerdonk FL, Joosten LAB, Notebaart RA, Ardavín C, Netea MG (2017) Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis. PLoS Pathog 13(9), e1006632.