(2024)
Single-cell RNA sequencing reveals HIF1A as a severity-sensitive immunological scar in circulating monocytes of convalescent comorbidity-free COVID-19 patients.
Cells 13(4),
300.
Prof. Dr. Christina Zielinski
Infection Immunology · Head +49 3641 532-1251 christina.zielinski@leibniz-hki.deCurriculum vitae
Main Research Areas
- Regulation of human T cells in physiological and pathological contexts
- Communication of human T cells with the tissue microenvironment
- Identification of pharmacological targets for T cell-based immunotherapies in chronic infections
Professional Career
| since 2021 | W3-Professorship (Chair of Department of Infection Immunology) at the Leibniz Institute for Natural Product Research and Infection Biology (Hans Knöll Institute), University of Jena |
| 2015 - 2020 | Professorship of the German Center for Infection Research (DZIF) at the Technical University of Munich |
| 2011 – 2015 | Clinical training in dermatology and allergology at the Charité–Universitätsmedizin Berlin (Department of Dermatology) and Clinical Scientist Track Program of the Berlin-Brandenburg School for Regenerative Therapies, Board certification 2015 |
| 2008 – 2011 | Postdoctoral training (DFG fellowship) at the Institute for Research in Biomedicine (IRB), Bellinzona, Switzerland (Supervisor: Federica Sallusto, PhD) |
| 2006 – 2008 | Clinical training in dermatology at the University of Tübingen (Head of department: Prof. Dr. med. M. Röcken) |
| 2007 | Doctor of Medicine (summa cum laude): “Intrinsic T cell defects in a mouse model of systemic lupus erythematosus“ |
| 2006 | Approbation (license to practice medicine) |
| 1999 – 2006 | Medical School at the University of Heidelberg (1 Semester Harvard Medical School, 1 Semester Duke Medical School), Scholar of the German National Academic Foundation (Studienstiftung des deutschen Volkes) |
Awards · Appointments · Scientific Activities
| 2023 | Elected Board member of the Germany Society for Immunology (DGFI) |
| 2023 | Member of the Editorial Board of the European Journal of Immunology |
| 2023 | Organizer of the German-Japanese Immunology Alliance |
| 2020 | Paul Langerhans Preis der Arbeitsgemeinschaft Dermatologische Forschung |
| 2019 | Ingrid zu-Solms Preis für Medizin |
| 2019 | Deutscher Neurodermitis Preis der Deutschen Dermatologischen Gesellschaft |
| 2015 | Vortragspreis auf dem International Congress on Autoinflammation, Dresden |
| 2014 | Forschungspreis der Deutschen Gesellschaft für Rheumatologie |
| 2014 | Silver Award der LEO Pharma Research Foundation für außerordentliche Beiträge zur Dermatologischen Forschung (European Society for Dermatological Research, ESDR) |
| 2014 | Wolfgang-Schulze Preis (Deutsche Rheuma-Liga) |
| 2013 | Oscar-Gans-Förderpreis (wichtigster Preis für dermatologische Forschung in Deutschland) |
| 2013 | Paul Janssen-Preis für Dermatologie und Immunologie der Deutschen Dermatologischen Gesellschaft |
| 2013 | Forschungspreis der Berliner Gesellschaft für Dermatologie |
| 2012 | Robert-Koch-Postdoktorandenpreis für Immunologie |
| 2012 | Nils-Ilja-Richter-Preis der Deutschen Gesellschaft für Autoimmun-Erkrankungen |
| 2012 | Celgene Award for Innovation in Inflammation and Immunology Research into Dermatological Diseases (bester europäischer Beitrag zur Dermatologie durch Nachwuchsforscher, European Society for Dermatological Research) |
| 2011 | Vortragspreis, European Academy and Clinical Immunology Conference, Istanbul |
| 2011 | gewähltes Mitglied der ‘ESDR Academy for Future Leaders in Dermatology’ |
| 2011 | Posterpreis, Schweizerische Gesellschaft für Allergologie und Immunologie, Lugano |
| 2010 | Posterpreis, Jahrestagung der Deutschen Gesellschaft für Immunologie, Leipzig |
| 2010 | Vortragspreis, World Immune Regulation Meeting, Davos |
Topics
Publications
(2024)
The impact of high salt diet on asthma in humans and mice: effect on specific T-cell signatures and microbiome.
Allergy 79(7),
1844-1857.
(2024)
Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity.
Nat Immunol 25(10),
1830-1844.
(2023)
Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation.
Nat Immunol 24(2),
295-308.
(2023)
A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity.
Cancer Cell 41(8),
1498-1515.
(2023)
T helper cell subsets: diversification of the field.
Eur J Immunol 53(12),
e2250218.
(Review)
(2022)
Human skin-resident host T cells can persist long term after allogeneic stem cell transplantation and maintain recirculation potential.
Sci Immunol 7(67),
eabe2634.
(2022)
A scoping review of regulatory T cell dynamics in convalescent COVID-19 patients – indications for their potential involvement in the development of Long COVID?
Front Immunol 13,
1070994.
(Review)
(2022)
Meeting Report: 47th Annual Meeting of the "Arbeitsgemeinschaft Dermatologische Forschung".
Exp Dermatol 31(10),
1641-1651.
(Review)
(2022)
A20 and ABIN-1 cooperate in balancing CBM complex-triggered NF-κB signaling in activated T cells.
Cell Mol Life Sci 79(2),
112.
