Curriculum vitae

Main Research Areas
  • Immunology and infection biology of pathogenic fungi
  • In vivo and ex vivo infection models
  • Mucosal pathogen-host-interaction
Professional Career
since 2014 Professor for Microbial Immunology, FSU Jena
since 2013 Head of the research group "Microbial Immunology", HKI Jena
2013 Habilitation and Venia legendi in microbiology, Friedrich-Schiller-University Jena
2007-2013 Head of the working group "Infection Models" within the department of Microbial Pathogenicity Mechanisms, HKI Jena, Deputy Supervisor
2007 Veterinary surgeon specialising in microbiology
2005-2007 Research assistant (postdoc) at the Institute for Microbiology, University of Veterinary Medicine, Hanover, within the SFB 587 (immune reaction of the lungs in case of infection and allergy, project A4)
2002-2005 PhD studies at the University of Veterinary Medicine, Hanover, project: "molecular mechanisms of the adaptation of Actinobacillus pleuropneumoniae to the respiratory tract of pigs" (DFG Research Training Group 745: Mucosal host-pathogen-interaction), PhD degree summa cum laude
2001 Veterinary license
1995-2001 Studies in veterinary medicine in Hanover and Pretoria, South Africa
Awards · Appointments · Scientific Activities
since 2013 Note taker within the specialist group "eukaryotic pathogens", Deutsche Gesellschaft für Hygiene und Mikrobiologie (DGHM)
2013 Co-organiser FEBS Advanced Practical Course "state-of-the-art infection models for human pathogenic fungi"
since 2012 Academic editor for PLoS One and Medical Mycology Case Reports
2010-2013 Deputy member of the advisory panel in accordance with § 15 clause 1 Animal Welfare Act, Thuringia
2007 Partial fellowship for taking part in the course molecular mycology: current approaches to fungal pathogenesis, Woods Hole, USA
2005 Award in veterinary medicine from the Kurt-Alten-Foundation for the best PhD-thesis
2001-2004 Fellow at the DFG’s research training group 745
2000 Full fellowship (The Wellcome Trust) at the summer school: fundamentals of veterinary science, University of Cambridge, UK
1998 Awards from the H. Wilhelm Schaumann Stiftung zu Hamburg for the best student achievements
1995-2001 Fellow at the Studienstiftung des deutschen Volkes

Publications

Mentrup T, Stumpff-Niggemann AY, Leinung N, Schlosser C, Schubert K, Wehner R, Tunger A, Schatz V, Neubert P, Gradtke AC, Wolf J, Rose-John S, Saftig P, Dalpke A, Jantsch J, Schmitz M, Fluhrer R, Jacobsen ID, Schröder B (2022) Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis. Nat Commun 13(1), 1880.
Ramírez-Zavala B, Krüger I, Dunker C, Jacobsen ID, Morschhäuser J (2022) The protein kinase Ire1 has a Hac1-independent essential role in iron uptake and virulence of Candida albicans. PLoS Pathog 18(2), e1010283.
Arastehfar A, Carvalho A, Houbraken J, Lombardi L, Garcia-Rubio R, Jenks JD, Rivero-Menendez O, Aljohani R, Jacobsen ID, Berman J, Osherov N, Hedayati MT, Ilkit M, Armstrong-James D, Gabaldón T, Meletiadis J, Kostrzewa M, Pan W, Lass-Flörl C, Perlin DS, Hoenigl M (2021) Aspergillus fumigatus and aspergillosis: From basics to clinics. Stud Mycol 100, 100115. (Review)
d'Enfert C, Kaune AK, Alaban LR, Chakraborty S, Cole N, Delavy M, Kosmala D, Marsaux B, Fróis-Martins R, Morelli M, Rosati D, Valentine M, Xie Z, Emritloll Y, Warn PA, Bequet F, Bougnoux ME, Bornes S, Gresnigt MS, Hube B, Jacobsen ID, Legrand M, Leibundgut-Landmann S, Manichanh C, Munro CA, Netea MG, Queiroz K, Roget K, Thomas V, Thoral C, Van den Abbeele P, Walker AW, Brown AJP (2021) The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives. FEMS Microbiol Rev 45(3), fuaa060. (Review)
Dunker C, Polke M, Schulze-Richter B, Schubert K, Rudolphi S, Gressler AE, Pawlik T, Prada Salcedo JP, Niemiec MJ, Slesiona-Künzel S, Swidergall M, Martin R, Dandekar T, Jacobsen ID (2021) Rapid proliferation due to better metabolic adaptation results in full virulence of a filament-deficient Candida albicans strain. Nat Commun 12(1), 3899.
Ferreira-Gomes M, Wich M, Böde S, Hube B, Jacobsen ID, Jungnickel B (2021) B cell recognition of Candida albicans hyphae via TLR 2 promotes IgG1 and IL-6 secretion for TH17 differentiation. Front Immunol 12, 698849.
Machata S, Sreekantapuram S, Hünniger K, Kurzai O, Dunker C, Schubert K, Krüger W, Schulze-Richter B, Speth C, Rambach G, Jacobsen ID (2021) Significant differences in host-pathogen interactions between murine and human whole blood. Front Immunol 11, 565869.
Wich M, Greim S, Ferreira-Gomes M, Krüger T, Kniemeyer O, Brakhage AA, Jacobsen ID, Hube B, Jungnickel B (2021) Functionality of the human antibody response to Candida albicans. Virulence 12(1), 3137-3148.
Birštonas L, Dallemulle A, López-Berges MS, Jacobsen ID, Offterdinger M, Abt B, Straßburger M, Bauer I, Schmidt O, Sarg B, Lindner H, Haas H, Gsaller F (2020) Multiplex genetic engineering exploiting pyrimidine salvage pathway-based endogenous counterselectable markers. mBio 11(2), e00230-20.
Gerwien F, Dunker C, Brandt P, Garbe E, Jacobsen ID, Vylkova S (2020) Clinical Candida albicans vaginal isolates and a laboratory strain show divergent behaviors during macrophage interactions. mSphere 5(4), e00393-20.