(2017)
Aspergillus fumigatus morphology and dynamic host interactions.
Nat Rev Microbiol 15(11),
661-674.
Dr. Mark Gresnigt
Adaptive Pathogenicity Strategies · Head +49 3641 532-1305 mark.gresnigt@leibniz-hki.deCurriculum vitae
Main Research Areas
- Infection biology of human pathogenic fungi (Candida albicans)
- Immunology of fungal infections
- Host-pathogen interactions
- Fungal adaptation to the host
Professional Career
| Since 05/2020 |
Junior Research Group Leader, Leibniz Institute of Natural Product Research and Infection Biology - Hans Knoell Institute, Adaptive Pathogenicity Strategies |
| 05/2018- 05/2020 |
Alexander von Humboldt Foundation Postdoctoral Fellowship, Leibniz Institute of Natural Product Research and Infection Biology - Hans Knoell Institute, Dept. Microbial Pathogenicity Mechanisms |
| 03/2018-04/2018 | Language Course German, Dresden, Germany |
| 08/2015-03/2018 | Postdoctoral researcher, Radboud University Medical Center, Department of Internal medicine, Nijmegen Institute for Infectious Diseases. Project: The development of novel immunomodulatory strategies for disseminated fungal infections |
| 10/2010-05/2015 | Phd, Radboud University Nijmegen Medical Center, department of internal medicine, Nijmegen, The Netherlands. Project: Pattern recognition and cytokine signalling pathways in the host defence against Aspergillus fumigatus |
| 02/2008-08/2010 | M.Sc. Medical Biology, Radboud University, Nijmegen, The Netherlands |
| 07/2003-07/2007 | B.Sc. Biology and Medical Laboratory Research, Saxion University of Applied Sciences, Enschede, The Netherlands |
Awards · Appointments · Scientific Activities
| 2021 | Research award of the German speaking society for Mycology (DMykG) |
| 2021 | Science Award Life Sciences and Physics 2021 Beutenberg Campus e.V. Jena |
| Since 2021 | Member and PI of the DFG SFB/TR 124 programme "Pathogenic fungi and their human host: Networks of interaction – FungiNet'" |
| Since 2020 | DFG Emmy Noether grant |
| 2020 | Journal of Fungi Travel Award |
| 2020 | Co-Organizer of the FEBS advanced practical course “State-of-the-art infection models for human pathogenic fungi” in Jena, Germany |
| 2019 | PLoS Pathogens Postdoctoral Poster Award, Advanced lecture course on Human Fungal Pathogens |
| 2019 | ESCMID Research Grant 2019 |
| 2019 | Co-organizer of the winter school of the FunHoMic Marie Curie International Training Network |
| 2018-2021 | Two publication awards of the Deutschsprachigen Mykologischen Gesellschaft (DMykG; as co-author) |
| 2018 | Humboldt Research Fellowship for Postdoctoral Researchers |
| 2018 | Golden pipette award by the Laboratory for Experimental Internal Medicine Radboud University Nijmegen Medical center |
| 2016 | 3rd prize for best thesis by the Radboud institute for molecular life sciences (RIMLS) |
| 2015 | Van Beckum thesis Award for best PhD thesis in the field of immunology by the Dutch society for Immunology (NVVI) |
| 2015 | Youth development Prize by the German speaking society for Mycology (DMykG) |
| Since 2014 | Ad hoc reviewer for 19 journals eLife, PLoS Pathogens, mBio, Journal of Infectious Diseases, Frontiers Immunology, Cellular Microbiology, FEMS microbiology letters, Microbial Pathogenesis, Virulence, and others |
| 2013 | ALLFUN Investigators Award |
Publications
(2017)
Personalized medicine in influenza: a bridge too far or the near future?
Curr Opin Pulm Med 23(3),
237-240.
(2016)
Aspergillus cell wall melanin blocks LC3-associated phagocytosis to promote pathogenicity.
Cell Host Microbe 19(1),
79-90.
(2016)
Aspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway.
mBio 7(3),
(2016)
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis.
Nat Immunol 17(4),
406-413.
(2016)
Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor.
Sci Rep 6,
26490.
(2016)
Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells.
Eur J Immunol 46(11),
2574-2586.
(2016)
Integrated transcriptomic and proteomic analyses of P. falciparum gametocytes: molecular insight into sex-specific processes and translational repression.
Nucleic Acids Res 44(13),
6087-6101.
(2016)
LC3-associated phagocytosis: a crucial mechanism for antifungal host defence against Aspergillus fumigatus.
Cell Microbiol 18(9),
1208-1216.
(2015)
Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors.
J Infect Dis 211(6),
978-987.
