Dr. Zoltán Cseresnyés

Applied Systems Biology · PolyTarget +49 3641 532-1532 zoltan.cseresnyes@leibniz-hki.de

Curriculum vitae

Main Research Areas

Intravital 2-photon microscopy of the immune system
Software development for automated and advanced image analysis and model-based simulations
Image-based Systems Biology

Professional Career

since 2016	Research associate, imaging and image analysis specialist at the Hans Knoell Institute, Jena
2016-2016	Microscopy and imaging specialist at the Deutsches Rheuma-Forschungszentrum (DRFZ) and the Beuth Hochschule, Berlin
2012-2016	Microscopy and imaging specialist in the JIMI (Joint Intravital Microscopy and Imaging) project at the Deutsches Rheuma-Forschungszentrum, Max Delbrück Center (Berlin) and at the Hans Knoell Institute, Jena
2010-2012	Research associate and Co-manager of the Confocal and 2-Photon Microscopy Core Facility at Max Delbrück Center for Molecular Medicine in Berlin
2007-2010	Imaging Facility manager in the Department of Zoology at the University of Cambridge (GB)
1994-2007	Research associate and confocal imaging specialist in the Department of Biochemistry and Molecular Biology at the University of Maryland Baltimore (USA)
1991-1994	Research associate in the Department of Physiology at the School of Medicine at Debrecen University (HU)
1985-1991	Research associate in the Department of Solid State Physics at Debrecen University (HU)

Publications

Hassan MIA, Kruse JM, Krüger T, Dahse HM, Cseresnyés Z, Blango MG, Slevogt H, Hörhold F, Ast V, König R, Figge MT, Kniemeyer O, Brakhage AA, Voigt K (2020) Functional surface proteomic profiling reveals the host heat-shock protein A8 as a mediator of Lichtheimia corymbifera recognition by murine alveolar macrophages. Environ Microbiol 22(9), 3722-3740.

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Medyukhina A^*, Blickensdorf M^*, Cseresnyés Z, Ruef N, Stein JV, Figge MT; ^* authors contributed equally (2020) Dynamic spherical harmonics approach for shape classification of migrating cells. Sci Rep 10(1), 6072.

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Schicke E, Cseresnyes Z, Rennert K, Vau V, Haupt KF, Hornung F, Nietzsche S, Swiczak F, Schmidtke M, Koch M, Glück B, Schacke M, Heller R, Mosig AS, Figge MT, Ehrhardt C, Löffler B, Deinhardt-Emmer S (2020) Staphylococcus aureus lung infection results in down-regulation of surfactant protein-A mainly caused by pro-inflammatory macrophages. Microorganisms 8(4), 577.

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Schmidt F, Thywißen A, Goldmann M, Cunha C, Cseresnyés Z, Schmidt H, Rafiq M, Galiani S, Gräler MH, Chamilos G, Lacerda JF, Campos Jr A, Eggeling C, Figge MT, Heinekamp T, Filler SG, Carvalho A, Brakhage AA (2020) Flotillin-dependent lipid-raft microdomains are required for functional phagolysosomes against fungal infections. Cell Rep 32(7), 108017.

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Shopova IA, Belyaev I, Dasari P, Jahreis S, Stroe MC, Cseresnyés Z, Zimmermann AK, Medyukhina A, Svensson C-M, Krüger T, Szeifert V, Nietzsche S, Conrad T, Blango MG, Kniemeyer O, von Lilienfeld-Toal M, Zipfel PF, Ligeti E, Figge MT, Brakhage AA (2020) Human neutrophils produce antifungal extracellular vesicles against Aspergillus fumigatus. mBio 11(2), e00596-20.

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Hassan MIA^*, Cseresnyes Z^*, Al-Zaben N, Dahse HM, Vilela de Oliveira RJ, Walther G, Voigt K^*^*, Figge MT^*^*; ^*shared first authors; ^*^* authors contributed equally (2019) The geographical region of origin determines the phagocytic vulnerability of Lichtheimia strains. Environ Microbiol 21(12), 4563-4581.

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Maurer M, Gresnigt MS, Last A, Wollny T, Berlinghof F, Pospich R, Cseresnyes Z, Medyukhina A, Graf K, Gröger M, Raasch M, Siwczak F, Nietzsche S, Jacobsen ID, Figge MT, Hube B, Huber O, Mosig AS (2019) A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies. Biomaterials 220, 119396.

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Cseresnyes Z^*, Kraibooj K^*, Figge MT, ^*authors contributed equally (2018) Hessian-based quantitative image analysis of host- pathogen confrontation assays. Cytometry A 93(3), 346-356.

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Dasari P, Shopova IA, Stroe M, Wartenberg D, Dahse HM, Beyersdorf N, Hortschansky P, Dietrich S, Cseresnyés Z, Figge MT, Westermann M, Skerka C, Brakhage AA, Zipfel PF (2018) Aspf2 from Aspergillus fumigatus recruits human immune regulators for immune evasion and cell damage. Front Immunol 9, 1635.

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Kriegel FL, Köhler R, Bayat Sarmadi J, Bayerl S, Hauser AE, Niesner R, Luch A^*, Cseresnyés Z^*, ^*authors contributed equally (2018) Morphology-based distinction between healthy and pathological cells utilizing fourier transforms and self-organizing maps. J Vis Exp 140, e58543.

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